Evolution of polyketide synthesis in a Dothideomycete forest pathogen
Fungal secondary metabolites have many important biological roles and some, like the toxic
polyketide aflatoxin, have been intensively studied at the genetic level. Complete sets of …
polyketide aflatoxin, have been intensively studied at the genetic level. Complete sets of …
Integration of chemical, genetic, and bioinformatic approaches delineates fungal polyketide–peptide hybrid biosynthesis
M Yokoyama, Y Hirayama, T Yamamoto… - Organic …, 2017 - ACS Publications
To identify natural products and their associated biosynthetic genes from underutilized,
difficult-to-manipulate microbes, chemical screening and bioinformatic analysis were …
difficult-to-manipulate microbes, chemical screening and bioinformatic analysis were …
Assembly of high‐quality genomes of the locoweed Oxytropis ochrocephala and its endophyte Alternaria oxytropis provides new evidence for their symbiotic …
L Zhang, R Wu, LAJ Mur, C Guo, X Zhao… - Molecular Ecology …, 2023 - Wiley Online Library
Locoweeds are perennial forbs poisonous to livestock and cause extreme losses to animal
husbandry. Locoweed toxicity is attributed to the symbiotic endophytes in Alternaria sect …
husbandry. Locoweed toxicity is attributed to the symbiotic endophytes in Alternaria sect …
Polyketide Synthase and Nonribosomal Peptide Synthetase Gene Clusters in Type Strains of the Genus Phytohabitans
H Komaki, T Tamura - Life, 2020 - mdpi.com
(1) Background: Phytohabitans is a recently established genus belonging to rare
actinomycetes. It has been unclear if its members have the capacity to synthesize diverse …
actinomycetes. It has been unclear if its members have the capacity to synthesize diverse …
Polyketide synthases of Diaporthe helianthi and involvement of DhPKS1 in virulence on sunflower
Background The early phases of Diaporthe helianthi pathogenesis on sunflower are
characterized by the production of phytotoxins that may play a role in host colonisation. In …
characterized by the production of phytotoxins that may play a role in host colonisation. In …
Polyketide synthase–nonribosomal peptide synthetase hybrid enzymes of fungi
S Kishimoto, Y Hirayama, K Watanabe - Physiology and Genetics …, 2018 - Springer
Fungi are known to produce various nonribosomal peptide-derived compounds that exhibit
useful bioactivities. However, understanding of how those fungal secondary metabolites are …
useful bioactivities. However, understanding of how those fungal secondary metabolites are …
Functional Analysis of All Nonribosomal Peptide Synthetases in Cochliobolus heterostrophus Reveals a Factor, NPS6, Involved in Virulence and Resistance to …
BN Lee, S Kroken, DYT Chou, B Robbertse… - Eukaryotic …, 2005 - Am Soc Microbiol
Nonribosomal peptides, made by nonribosomal peptide synthetases, have diverse
biological activities, including roles as fungal virulence effectors. Inspection of the genome of …
biological activities, including roles as fungal virulence effectors. Inspection of the genome of …
Identification of the nonribosomal peptide synthetase gene responsible for bassianolide synthesis in wood-decaying fungus Xylaria sp. BCC1067
J Jirakkakul, J Punya, S Pongpattanakitshote… - …, 2008 - microbiologyresearch.org
Intensive study of gene diversity of bioactive compounds in a wood-rot fungus, Xylaria sp.
BCC1067, has made it possible to identify polyketides and nonribosomal peptides (NRPs) …
BCC1067, has made it possible to identify polyketides and nonribosomal peptides (NRPs) …
Efficient disruption of a polyketide synthase gene (pks1) required for melanin synthesis through Agrobacterium-mediated transformation of Glarea lozoyensis
A Zhang, P Lu, AM Dahl-Roshak, PS Paress… - Molecular Genetics and …, 2003 - Springer
Glarea lozoyensis produces pneumocandin B 0, a potent inhibitor of fungal glucan
synthesis. This industrially important filamentous fungus is slow-growing, is very darkly …
synthesis. This industrially important filamentous fungus is slow-growing, is very darkly …
Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products
X Wang, X Zhang, L Liu, M Xiang, W Wang, X Sun… - BMC genomics, 2015 - Springer
Background In recent years, the genus Pestalotiopsis is receiving increasing attention, not
only because of its economic impact as a plant pathogen but also as a commonly isolated …
only because of its economic impact as a plant pathogen but also as a commonly isolated …