The contribution of regulatory T cells (Treg) to the induction and maintenance of tolerance is
well-recognized in rodents and may contribute to long-term human organ allograft survival …

Adoptive therapy with regulatory T cells (Tregs) has shown great promises in many
experimental models to induce permanent graft acceptance and tolerance to alloantigens …

Owing to the adverse effects of immunosuppression and an inability to prevent chronic
rejection, there is a pressing need for alternative strategies to control alloimmunity. In three …

Regulatory T cells (Tregs) play an important role in immunoregulation and have been shown
in animal models to promote transplantation tolerance and curb autoimmunity following their …

The concept of regulatory T cell (Treg) therapy in transplantation is now a reality. Significant
advances in science and technology have enabled us to isolate human Tregs, expand them …

Receiving a kidney transplant currently requires patients to commit to life-long
immunosuppression therapy. The combination of immunosuppressive drugs currently taken …

Graft survival has been lately improved by the introduction of efficient immunosuppressive
drugs. However, late graft loss caused by chronic rejection and the side effects of long‐term …

Organ transplantation is the optimal treatment for terminal and irreversible organ failure.
Achieving transplantation tolerance has long been the ultimate goal in the field of …

Adoptive regulatory T cell therapy: challenges in clinical t... : Current Opinion in Organ
Transplantation Adoptive regulatory T cell therapy: challenges in clinical transplantation : Current …

Transplantation is a successful treatment for end-stage organ failure. Despite improvements
in short-term outcome, long-term survival remains suboptimal because of the morbidity and …