The inability of neurons to undergo mitosis renders damage to the central or peripheral
nervous system. Neural stem cell therapy could provide a path for treating the …

Developing a three-dimensional (3D) neural tissue model is important to comprehensively
understand neural development and neuronal degeneration associated with various …

When a single neuron is cultured in isolation from other neurons, its axon connects with its
own dendrites to form a simple, independent network with no synaptic inputs from other …

Compartmentalized cell cultures (CCCs) provide the possibility to study mechanisms of
neurodegenerative diseases, such as spreading of misfolded proteins in Alzheimer's or …

Neural stem cell (NSC) transplantation has great therapeutic potential for
neurodegenerative diseases and central nervous system injuries. Successful NSC …

To improve our understanding of how the central nervous system functions in health and
disease, we report the development of an integrated chip for studying the effects of the …

Microfluidics devices for co-culturing neurons and oligodendrocytes represent an important
in vitro research tool to decipher myelination mechanisms in health and disease and in the …

Over the past few decades, micromachined chips such as microfluidic systems are making a
big impact on neuroscience research and the industry due to their low-cost potential and …

Microfluidics can provide unique experimental tools to visualize the development of neural
structures within a microscale device, which is followed by guidance of neurite growth in the …

Obtaining single dissociated cells from neurospheres is difficult using nonenzymatic
methods. In this paper we report the development of a microfluidic-chip-based approach that …