Issues in blood pressure control and the potential role of single‐pill combination therapies

M Burnier, RE Brown, SH Ong… - … journal of clinical …, 2009 - Wiley Online Library
Hypertension (HTN) is a major risk factor for cardiovascular mortality, yet only a small
proportion of hypertensive individuals receive appropriate therapy and achieve target blood …

Recent Developments in Drug Targets and Combination Therapy for the Clinical Management of Hypertension

PK Niranjan, S Bahadur - Cardiovascular & Haematological …, 2023 - ingentaconnect.com
Raised blood pressure is the most common complication worldwide that may lead to
atherosclerosis and ischemic heart disease. Unhealthy lifestyles, smoking, alcohol …

Emerging Insights in the First‐Step Use of Antihypertensive Combination Therapy

K Norris, JM Neutel - The Journal of Clinical Hypertension, 2007 - Wiley Online Library
The blood pressure (BP) goals set by hypertension management guidelines (< 140/90 mm
Hg in uncomplicated hypertension;< 130/80 mm Hg in type 2 diabetes or kidney disease) …

[PDF][PDF] CONTEMPORARY MANAGEMENT OF HYPERTENSION

D Grekova, K Andreevska, R Staynova, V Madzharov… - researchgate.net
Introduction: Hypertension or high blood pressure can lead to severe complications and
increases the risk of heart disease, stroke, and cause death. Hypertension and heart …

[引用][C] What is the role of combination therapy in treating hypertension

C Vlachopoulos, P Xaplanteris - Dialogues Cardiovasc Med, 2015

Comparative effectiveness of monotherapies and combination therapies for patients with hypertension: protocol for a systematic review with network meta-analyses

B Hutton, J Tetzlaff, F Yazdi, J Thielman, S Kanji… - Systematic reviews, 2013 - Springer
Background Hypertension has been cited as the most common attributable risk factor for
death worldwide, and in Canada more than one of every five adults had this diagnosis in …

More medications, fewer pills: combination medications for the treatment of hypertension

R Lewanczuk, SW Tobe - Canadian journal of cardiology, 2007 - Elsevier
Achieving blood pressure targets in hypertension can be challenging. Often, patients require
multiple medications to reach these targets. The Canadian Hypertension Education Program …

Combination drug treatment of hypertension: have we come full circle?

AA Taylor - Current Cardiology Reports, 2004 - Springer
Only 30% of hypertensive patients achieved and maintained adequate blood pressure
control on a single drug in recent clinical trials. For the majority of patients who require two …

Creating a combination antihypertensive regimen: what does the research show?

MA Weber - The Journal of Clinical Hypertension, 2003 - Wiley Online Library
Major randomized clinical trials have demonstrated unquestionable clinical benefits of
lowering blood pressure without establishing superiority of any specific antihypertensive …

Rationale for combination therapy in hypertension management: focus on angiotensin receptor blockers and thiazide diuretics

DT Nash - Southern medical journal, 2007 - go.gale.com
Despite recognition that hypertension is a major risk factor for cardiovascular events and
mortality, blood pressure control rates remain low in the US population. Reflecting clinical …