The goal of antihypertensive therapy is to reduce the risk associated with blood pressure
elevation. Although the choice of first-line drug therapy may exert some effects on different …

Hypertension is a major cause of cardiovascular disease and deaths worldwide especially
in low-and middle-income countries. Despite the availability of safe, well-tolerated, and cost …

The goal of antihypertensive therapy is to abolish the risks associated with blood pressure
(BP) elevation without adversely affecting quality of life. Control of hypertension and …

In the late 1960s and early 1970s, Freis et al. demonstrated convincingly that the
administration of antihypertensive drugs was associated with a marked reduction in target …

Editor's Note: The American Society of Hypertension is publishing a series of Position
Papers in their official journals throughout the 2008–2011 years. The following Position …

The history of antihypertensive therapy extends over half a century, during which time
numerous clinical studies have established that strict control of blood pressure results in …

Hypertension is a multifactorial disorder leading to pathophysiologic changes in target
organs over time through diverse mechanisms. In addition, hypertension frequently resists …

In this short review, we present a historical perspective of the treatment of hypertension,
highlight some current issues and look to the possible future of antihypertensive therapy …

Both in clinical practice and in drug trials, combination treatment of hypertension plays a
fundamental role. This article reviews the features that make combined therapy with two …