Defining genomic, transcriptomic, proteomic, epigenetic, and phenotypic biomarkers with prognostic capability in male breast cancer: a systematic review

S Chatterji, E Krzoska, CW Thoroughgood… - The Lancet …, 2023 - thelancet.com
Although similar phenotypically, there is evidence that male and female breast cancer differ
in their molecular landscapes. In this systematic review, we consolidated all existing …

The genomic landscape of male breast cancers

S Piscuoglio, CKY Ng, MP Murray… - Clinical Cancer …, 2016 - AACR
Purpose: Male breast cancer is rare, and its genomic landscape has yet to be fully
characterized. Lacking studies in men, treatment of males with breast cancer is extrapolated …

The cancer genetics and pathology of male breast cancer

S Deb, SR Lakhani, L Ottini, SB Fox - Histopathology, 2016 - Wiley Online Library
Male breast cancer (MBC) is an uncommon and poorly understood disease. Recent
molecular studies have shown important differences from female breast cancer which are …

Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer

M Callari, V Cappelletti, L De Cecco, V Musella… - Breast cancer research …, 2011 - Springer
Male breast cancer (MBC) is a poorly characterized disease because of its rarity. Clinical
management is based on results obtained from randomized trials conducted in women …

[HTML][HTML] Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification

R Kornegoor, CB Moelans… - Breast cancer research …, 2012 - Springer
Gene amplification is an important mechanism for oncogene activation, a crucial step in
carcinogenesis. Compared to female breast cancer, little is known on the genetic makeup of …

[HTML][HTML] Molecular profiling of male breast cancer–lost in translation?

I Johansson, F Killander, B Linderholm… - The international journal …, 2014 - Elsevier
Breast cancer is the most common cancer form in women and it has been extensively
studied on the molecular level. Male breast cancer (MBC), on the other hand, is rare and has …

A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

AM Shaaban, GR Ball, RA Brannan, G Cserni… - Breast cancer research …, 2012 - Springer
Male breast cancer remains understudied despite evidence of rising incidence. Using a co-
ordinated multi-centre approach, we present the first large scale biomarker study to define …

[HTML][HTML] The landscape of candidate driver genes differs between male and female breast cancer

I Johansson, M Ringnér, I Hedenfalk - PloS one, 2013 - journals.plos.org
The rapidly growing collection of diverse genome-scale data from multiple tumor types
sheds light on various aspects of the underlying tumor biology. With the objective to identify …

Male breast cancer: an update in diagnosis, treatment and molecular profiling

S Onami, M Ozaki, JE Mortimer, SK Pal - Maturitas, 2010 - Elsevier
Significant advances have been made in the diagnosis and treatment of female breast
cancer, resulting in a decline in incidence and a global improvement in clinical outcome …

[HTML][HTML] Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology

V Valentini, V Silvestri, A Bucalo, G Conti… - Frontiers in …, 2023 - frontiersin.org
Introduction Compared with breast cancer (BC) in women, BC in men is a rare disease with
genetic and molecular peculiarities. Therapeutic approaches for male BC (MBC) are …