Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease

BC Young, T Golubchik, EM Batty… - Proceedings of the …, 2012 - National Acad Sciences
Whole-genome sequencing offers new insights into the evolution of bacterial pathogens and
the etiology of bacterial disease. Staphylococcus aureus is a major cause of bacteria …

Evolution of Staphylococcus aureus during human colonization and infection

JR Fitzgerald - Infection, genetics and evolution, 2014 - Elsevier
The diversification of bacterial pathogens during infection is central to their capacity to adapt
to different anatomical niches, evade the host immune system, and overcome therapeutic …

Architecture of a species: phylogenomics of Staphylococcus aureus

PJ Planet, A Narechania, L Chen, B Mathema… - Trends in …, 2017 - cell.com
A deluge of whole-genome sequencing has begun to give insights into the patterns and
processes of microbial evolution, but genome sequences have accrued in a haphazard …

Within-Host Evolution of Staphylococcus aureus during Asymptomatic Carriage

T Golubchik, EM Batty, RR Miller, H Farr, BC Young… - PloS one, 2013 - journals.plos.org
Background Staphylococcus aureus is a major cause of healthcare associated mortality, but
like many important bacterial pathogens, it is a common constituent of the normal human …

Whole-Genome Sequencing of Staphylococcus haemolyticus Uncovers the Extreme Plasticity of Its Genome and the Evolution of Human-Colonizing Staphylococcal …

F Takeuchi, S Watanabe, T Baba, H Yuzawa… - Journal of …, 2005 - Am Soc Microbiol
Staphylococcus haemolyticus is an opportunistic bacterial pathogen that colonizes human
skin and is remarkable for its highly antibiotic-resistant phenotype. We determined the …

Population genetics and the evolution of virulence in Staphylococcus aureus

KYL Chua, BP Howden, JH Jiang, T Stinear… - Infection, Genetics and …, 2014 - Elsevier
Staphylococcus aureus is one of the most important human pathogens, causing life-
threatening infection in the community and hospital setting. The population genetics of S …

Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance

MTG Holden, EJ Feil, JA Lindsay… - Proceedings of the …, 2004 - National Acad Sciences
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its
genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains …

Microarrays Reveal that Each of the Ten Dominant Lineages of Staphylococcus aureus Has a Unique Combination of Surface-Associated and Regulatory Genes

JA Lindsay, CE Moore, NP Day, SJ Peacock… - Journal of …, 2006 - Am Soc Microbiol
Staphylococcus aureus is the most common cause of hospital-acquired infection. In healthy
hosts outside of the health care setting, S. aureus is a frequent colonizer of the human nose …

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia

SG Giulieri, SL Baines, R Guerillot, T Seemann… - Genome medicine, 2018 - Springer
Background Large-scale genomic studies of within-host diversity in Staphylococcus aureus
bacteraemia (SAB) are needed to understanding bacterial adaptation underlying …

Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing …

SR Gill, DE Fouts, GL Archer, EF Mongodin… - Journal of …, 2005 - Am Soc Microbiol
Staphylococcus aureus is an opportunistic pathogen and the major causative agent of
numerous hospital-and community-acquired infections. Staphylococcus epidermidis has …