Cysteinyldopas, metabolic by‐products of activated melanocytes, are photochemically
unstable in the presence of biologically relevant ultraviolet radiation (ie wavelengths> 300 …

We have recently demonstrated that cysteinyldopas, pheomelanogenic precursors and
excreted eumelanogenic metabolites, are photolabile and initiate DNA damage in vitro. In …

Normal melanocytes produce specialized subcellular organelles called melanosomes within
which the biochemical processes of melanogenesis occurs. During sunlight‐induced …

The photochemical behavior of 5‐S‐cysteinyldopa (5‐S‐CD), a colorless product of
melanocyte metabolism, was investigated in neutral phosphate buffer with biologically …

The survey focuses on recent aspects of photochemical reactions to cellular DNA that are
implicated through the predominant formation of mostly bipyrimidine photoproducts in …

A 1 m diameter water lens was used to focus solar radiation, giving an 8‐fold concentration
of the total spectrum and a cytocidal flux similar to that of laboratory UV sources. Survival …

The history and origin of the science of photobiology are reviewed. Interest in the biologic
effects of light gradually increased, beginning with the discovery of ultraviolet and infrared …

The premutagenic oxidative DNA base damage, 7, 8-dihydro-8-oxoguanine, is induced in
human skin fibroblasts by monochromatic radiation ranging from a UVB wavelength (312 …

Publisher Summary DNA damage induced by solar radiation in mammalian cells consists
largely of two types of modification: pyrimidine dimers and oxidative modifications …

DNA damage induced by UV radiation and visible light (290-500 nm) in AS52 Chinese
hamster cells was analysed by an alkaline elution assay with specific repair endonucleases …