[HTML][HTML] A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease
Genome-wide association studies (GWASs) have identified a number of genetic risk loci
associated with systemic sclerosis (SSc) and Crohn's disease (CD), some of which confer …
associated with systemic sclerosis (SSc) and Crohn's disease (CD), some of which confer …
[HTML][HTML] Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease
K Wang, H Zhang, S Kugathasan, V Annese… - The American Journal of …, 2009 - cell.com
Previous genome-wide association (GWA) studies typically focus on single-locus analysis,
which may not have the power to detect the majority of genuinely associated loci. Here, we …
which may not have the power to detect the majority of genuinely associated loci. Here, we …
[HTML][HTML] Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci
D Ellinghaus, E Ellinghaus, RP Nair, PE Stuart… - The American Journal of …, 2012 - cell.com
Psoriasis (PS) and Crohn disease (CD) have been shown to be epidemiologically,
pathologically, and therapeutically connected, but little is known about their shared genetic …
pathologically, and therapeutically connected, but little is known about their shared genetic …
Association study of 71 European Crohn's disease susceptibility loci in a Japanese population
A Hirano, K Yamazaki, J Umeno… - Inflammatory bowel …, 2013 - academic.oup.com
Background A large-scale meta-analysis of a series of European genome-wide association
studies revealed 71 susceptibility loci for Crohn's disease (CD). However, it is not clear …
studies revealed 71 susceptibility loci for Crohn's disease (CD). However, it is not clear …
[HTML][HTML] Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases
An epidemiological association between multiple sclerosis (MS) and inflammatory bowel
disease (IBD) is well established, but whether this reflects a shared genetic aetiology, and …
disease (IBD) is well established, but whether this reflects a shared genetic aetiology, and …
Genome-wide Association Study Signal at the 12q12 Locus for Crohn's Disease May Represent Associations with the MUC19 Gene
Background Genome-wide association studies (GWAS) in Crohn's disease (CD) have
identified associations with single-nucleotide polymorphism (SNP) rs11175593 at …
identified associations with single-nucleotide polymorphism (SNP) rs11175593 at …
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
A genome-wide association study identifies 2 susceptibility loci for Crohn's disease in a Japanese population
K Yamazaki, J Umeno, A Takahashi, A Hirano… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Crohn's disease is an inflammatory bowel disease induced by
multiple genetic and environmental factors. Genome-wide association studies have …
multiple genetic and environmental factors. Genome-wide association studies have …
Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility
Genome-wide association studies (GWAS) have identified hundreds of loci associated with
Crohns disease (CD), however, as with all complex diseases, deriving pathogenic …
Crohns disease (CD), however, as with all complex diseases, deriving pathogenic …
Genome‐wide association studies in Crohn's disease: past, present and future
B Verstockt, KGC Smith, JC Lee - Clinical & translational …, 2018 - Wiley Online Library
Over the course of the past decade, genome‐wide association studies (GWAS) have
revolutionised our understanding of complex disease genetics. One of the diseases that has …
revolutionised our understanding of complex disease genetics. One of the diseases that has …