Serial technetium-99m radionuclide ventriculograms, indium-111 antimyosin antibody scans
and tissue biodistribution studies were performed in C, H/He mice with experimentally …

We have developed murine models of viral myocarditis induced by encephalomyocarditis
(EMC) virus in which severe myocarditis, congestive heart failure and dilated …

Animal models of congestive heart failure and dilated cardiomyopathy following
encephalomyocarditis (EMC) virus infection have been developed. Differences were found …

LB Stull, NA DiIulio, M. Yu, CF McTiernan, NB Ratliff, VK Tuohy and C. Schomisch Moravec.
Alterations in Cardiac Function and Gene Expression during Autoimmune Myocarditis in …

The most important clinical manifestation of myocarditis is congestive heart failure. The
precise mechanisms of heart failure during myocarditis have not been elucidated because …

Cardiotropic virus infection of mice typically produces florid myocardial inflammation and, in
certain strains, elicits a chronic postinfectious autoimmune myocarditis. In humans …

Myocarditis is a disease process that is poorly understood. The incidence of myocarditis may
vary with age, sex, and season of the year. The pathogenesis of myocarditis has been …

We have developed two models of myocarditis in mice. The first is produced by infection with
Coxsackievirus B3; the second results from immunization with cardiac myosin. Both forms of …

Mechanistic studies of myocarditis have focused on cell culture and rodent models of
disease. These model systems have provided valuable insight into the mechanisms by …

Background. Infection with Coxsackievirus B3 induces myocarditis. We aimed to compare
the acute and chronic phases of viral myocarditis to identify the immediate effects of cardiac …