Genomics of antibiotic‐resistance prediction in Pseudomonas aeruginosa
Antibiotic resistance is a worldwide health issue spreading quickly among human and
animal pathogens, as well as environmental bacteria. Misuse of antibiotics has an impact on …
animal pathogens, as well as environmental bacteria. Misuse of antibiotics has an impact on …
Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning‐enabled molecular diagnostics
A Khaledi, A Weimann, M Schniederjans… - EMBO molecular …, 2020 - embopress.org
Limited therapy options due to antibiotic resistance underscore the need for optimization of
current diagnostics. In some bacterial species, antimicrobial resistance can be …
current diagnostics. In some bacterial species, antimicrobial resistance can be …
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes
J Jeukens, I Kukavica-Ibrulj… - FEMS microbiology …, 2017 - academic.oup.com
Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
A machine learning framework to predict antibiotic resistance traits and yet unknown genes underlying resistance to specific antibiotics in bacterial strains
Recently, the frequency of observing bacterial strains without known genetic components
underlying phenotypic resistance to antibiotics has increased. There are several strains of …
underlying phenotypic resistance to antibiotics has increased. There are several strains of …
Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments
Antibiotic resistance has become a serious threat to human health (WHO Antibacterial
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …
Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data
D Moradigaravand, M Palm, A Farewell… - PLoS computational …, 2018 - journals.plos.org
The emergence of microbial antibiotic resistance is a global health threat. In clinical settings,
the key to controlling spread of resistant strains is accurate and rapid detection. As …
the key to controlling spread of resistant strains is accurate and rapid detection. As …
A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas …
SJT Wardell, A Rehman, LW Martin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …
and chronic infections. An increasing number of isolates have mutations that make them …
A genomic data resource for predicting antimicrobial resistance from laboratory-derived antimicrobial susceptibility phenotypes
M VanOeffelen, M Nguyen, D Aytan-Aktug… - Briefings in …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) is a major global health threat that affects millions of people
each year. Funding agencies worldwide and the global research community have expended …
each year. Funding agencies worldwide and the global research community have expended …
Bioinformatics of antimicrobial resistance in the age of molecular epidemiology
AG McArthur, GD Wright - Current opinion in microbiology, 2015 - Elsevier
Highlights•Examination of antimicrobial resistance is transitioning from phenotype to
genotype.•Whole genome sequencing of pathogens will become a commonplace clinical …
genotype.•Whole genome sequencing of pathogens will become a commonplace clinical …
Transcriptome profiling of antimicrobial resistance in Pseudomonas aeruginosa
A Khaledi, M Schniederjans, S Pohl… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Emerging resistance to antimicrobials and the lack of new antibiotic drug candidates
underscore the need for optimization of current diagnostics and therapies to diminish the …
underscore the need for optimization of current diagnostics and therapies to diminish the …