Amiodarone was developed in the early 1960s based on extracts from the Khella plant and
was initially used as a coronary dilator for the treatment of angina pectoris (Singh 2008). In …

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Cardiac arrhythmias are a cause of significant morbidity and mortality in patients with
cardiac disease, and thus represent a major management problem. The recognition that …

Despite remarkable advances in the non-pharmacological treatment, a clear role exists for
antiarrhythmic drug therapy in the management of many common cardiac arrhythmias. The …

Amiodarone, an iodinated benzofuran derivative, introduced in 1960's as an anti-anginal
agent, emerged as a potent anti-arrhythmic agent by 1970's and is currently one of the most …

Amiodarone is an iodinated benzofuran derivative, a highly lipophilic drug with
unpredictable pharmacokinetics. Although originally classified as a class III agent due to its …

Ventricular arrhythmias still represent an important cause of morbidity and mortality,
especially in patients with heart failure and reduced left ventricular ejection fraction …

Amiodarone is a benzofuran derivative that has been effective for the treatment of both
supraventricular and ventricular tachyarrhythmias. It has a large volume of distribution …

Amiodarone is an antiarrhythmic agent commonly used in the treatment of supraventricular
and ventricular tachyarrhythmias. This article reviews the results and clinical implications of …

Introduced as an anti-anginal compound in 1962, amiodarone emerged in the 1970s as a
uniquely effective antiarrhythmic and antifibrillatory drug with a multiplicity of properties, the …