The obligate intracellular pathogen Chlamydia trachomatis (Ct) is the leading cause of
bacterial sexually transmitted infections and blindness globally. To date, Ct urogenital …

Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a
major public health concern. In vitro persistence is known to develop through interferon …

Chlamydia trachomatis is the leading cause of preventable blindness and the most common
bacterial sexually transmitted infection. Different strains are associated with ocular or …

A striking difference between genital and ocular clinical isolates of Chlamydia trachomatis is
that only the former express a functional tryptophan synthase and therefore can synthesize …

We previously reported that laboratory reference strains of Chlamydia trachomatis differing
in infection organotropism correlated with inactivating mutations in the pathogen's …

Different variants of the obligate intracellular bacterial pathogen Chlamydia trachomatis
cause the diseases trachoma and chlamydia. The trachoma strains cause chronic infections …

Chlamydia trachomatis (C. trachomatis) is the most common etiological agent of bacterial
sexually transmitted infections (STIs) and a worldwide public health issue. The natural …

The trp operon of Chlamydia trachomatis is organized differently from other model bacteria.
It contains trpR, an intergenic region (IGR), and the biosynthetic trpB and trpA open-reading …

During infection, pathogens are starved of essential nutrients such as iron and tryptophan by
host immune effectors. Without conserved global stress response regulators, how the …

Background Complete genomic sequences of closely related organisms, such as the
chlamydiae, afford the opportunity to assess significant strain differences against a …