Gene-environment interactions are known to play a major role in the ethiopathology of
several neuropsychiatric disorders, including Alzheimer's disease (AD). The present study …

Although the impacts of environmental enrichment (EE) in several genetic models of
Alzheimer's disease (AD) have been documented, the focus has remained predominantly on …

The triple-transgenic mouse line (3× Tg-AD) harboring PS1 M146V, APP Swe, and tau
p301L transgenes represents the only transgenic model for Alzheimer's disease (AD) to date …

Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by a progressive
loss of cognitive function. Despite considerable progress, a complete description of the …

The interaction between gene and environment is known to play a major role in the etiology
of several neuropsychiatric disorders, including Alzheimer's disease (AD). The present study …

Research has demonstrated that stress can exacerbate AD pathology in transgenic mouse
models of AD. The purpose of the present studies was to extend this work by determining …

In addition to memory impairments, patients with Alzheimer's disease (AD) exhibit a number
of behavioural and psychological symptoms that can affect social interactions over the …

Besides memory deficits, Alzheimer's disease (AD) patients suffer from neuropsychiatric
symptoms, including alterations in social interactions, which are subject of a growing …

Social withdrawal and agitation/aggression are common behavioral and psychological
symptoms of dementia presented by Alzheimer's disease (AD) patients, with males …

Transgenic mouse models of Alzheimer's disease (AD), such as the 3xTg-AD mice, are
instrumental for elucidating genetic, pharmacologic, environmental, and behavioral factors …