[HTML][HTML] Philadelphia-negative myeloproliferative neoplasms display alterations in monocyte subpopulations frequency and immunophenotype

VL Bassan, GD Barretto, FC de Almeida, PVB Palma… - Medical Oncology, 2022 - Springer
Philadelphia-negative myeloproliferative neoplasms (MPN) are clonal hematological
diseases associated with driver mutations in JAK2, CALR, and MPL genes. Moreover …

Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both

S Koschmieder, TI Mughal, HC Hasselbalch, G Barosi… - Leukemia, 2016 - nature.com
The Philadelphia-negative myeloproliferative neoplasms (MPNs) are clonal disorders
involving hematopoietic stem and progenitor cells and are associated with …

[HTML][HTML] The role of neutrophilic granulocytes in Philadelphia chromosome negative myeloproliferative neoplasms

D Kiem, S Wagner, T Magnes, A Egle, R Greil… - International Journal of …, 2021 - mdpi.com
Philadelphia chromosome negative myeloproliferative neoplasms (MPN) are composed of
polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF) …

Pathogenesis of myeloproliferative neoplasms: role and mechanisms of chronic inflammation

S Hermouet, E Bigot-Corbel… - Mediators of …, 2015 - Wiley Online Library
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of clonal diseases
characterized by the excessive and chronic production of mature cells from one or several of …

[HTML][HTML] Contributions of bone marrow monocytes/macrophages in myeloproliferative neoplasms with JAK2V617F mutation

W Fan, W Cao, J Shi, F Gao, M Wang, L Xu, F Wang… - Annals of …, 2023 - Springer
The classic BCR-ABL1-negative myeloproliferative neoplasm (MPN) is a highly
heterogeneous hematologic tumor that includes three subtypes, namely polycythemia vera …

Phenotypic characterization of disease‐initiating stem cells in JAK2‐ or CALR‐mutated myeloproliferative neoplasms

D Ivanov, JD Milosevic Feenstra… - American Journal of …, 2023 - Wiley Online Library
Myeloproliferative neoplasms (MPN) are characterized by uncontrolled expansion of
myeloid cells, disease‐related mutations in certain driver‐genes including JAK2, CALR, and …

[HTML][HTML] Philadelphia-negative myeloproliferative neoplasms as disorders marked by cytokine modulation

MC Cacemiro, JG Cominal, R Tognon… - … , transfusion and cell …, 2018 - SciELO Brasil
Background: Cytokines are key immune mediators in physiological and disease processes,
whose increased levels have been associated with the physiopathology of hematopoietic …

Flow cytometry immunophenotypic analysis of Philadelphia‐negative myeloproliferative neoplasms: Correlation with histopathologic features

J Ouyang, W Zheng, Q Shen… - Cytometry Part B …, 2015 - Wiley Online Library
Background Compared with the proven utility of flow cytometry immunophenotyping (FCI)
analysis in the workup of myelodysplastic syndromes (MDS), immunophenotypic alterations …

[HTML][HTML] Mediators of inflammation in myeloproliferative neoplasms: state of the art

S Hermouet, HC Hasselbalch, V Čokić - Mediators of Inflammation, 2015 - ncbi.nlm.nih.gov
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of chronic clonal diseases
which are characterized by the excessive production of mature cells of one or more of the …

[HTML][HTML] The allele burden of JAK2 V617F can aid in differential diagnosis of Philadelphia Chromosome-Negative Myeloproliferative Neoplasm

SH Park, HS Chi, YU Cho, S Jang, CJ Park - Blood research, 2013 - synapse.koreamed.org
Background We aimed to evaluate the feasibility of using the allele burden of Janus kinase 2
(JAK2) V617F as a criterion for discriminating 3 subtypes of Philadelphia chromosome …