Quorum sensing: a prospective therapeutic target for bacterial diseases

Q Jiang, J Chen, C Yang, Y Yin… - BioMed Research …, 2019 - Wiley Online Library
Bacterial quorum sensing (QS) is a cell‐to‐cell communication in which specific signals are
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …

[HTML][HTML] It is the time for quorum sensing inhibition as alternative strategy of antimicrobial therapy

NG Naga, DE El-Badan, KM Ghanem… - Cell Communication and …, 2023 - Springer
Multiple drug resistance poses a significant threat to public health worldwide, with a
substantial increase in morbidity and mortality rates. Consequently, searching for novel …

Bacterial quorum sensing: a new target for anti-infective immunotherapy

GF Kaufmann, J Park, KD Janda - Expert opinion on biological …, 2008 - Taylor & Francis
Background: Cell-to-cell communication via exchange of small molecules,'autoinducers', is a
widespread phenomenon among Gram-negative and-positive bacteria. This intercellular …

Quorum sensing inhibitors: a patent review (2014–2018)

X Chen, L Zhang, M Zhang, H Liu, P Lu… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Quorum sensing (QS) is a cell density-dependent phenomenon in which
specific pathways are activated after autoinducers (AIs) outside the microorganism reach a …

Developments in strategies for Quorum Sensing virulence factor inhibition to combat bacterial drug resistance

S Haque, F Ahmad, SA Dar, A Jawed, RK Mandal… - Microbial …, 2018 - Elsevier
Quorum sensing (QS) is a complex bacterial intercellular communication system. It is
mediated by molecules called auto-inducers (AIs) and allows coordinated responses to a …

Quorum sensing pathways in Gram-positive and-negative bacteria: potential of their interruption in abating drug resistance

S Haque, DK Yadav, SC Bisht, N Yadav… - Journal of …, 2019 - Taylor & Francis
Quorum sensing (QS) is an inter-cell communication between bacterial populations through
release of tiny diffusible compounds as signalling agents, called auto-inducers, abetting …

[HTML][HTML] Interference in bacterial quorum sensing: a biopharmaceutical perspective

B Rémy, S Mion, L Plener, M Elias… - Frontiers in …, 2018 - frontiersin.org
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

Quorum sensing inhibitors: a patent overview

J Pan, D Ren - Expert opinion on therapeutic patents, 2009 - Taylor & Francis
Background: Quorum sensing (QS) is a microbial cell–cell signaling system that correlates
gene expression with cell population density. It plays important roles in intra-species …

Interfering with bacterial quorum sensing

K Reuter, A Steinbach, V Helms - Perspectives in Medicinal …, 2016 - journals.sagepub.com
Quorum sensing (QS) describes the exchange of chemical signals in bacterial populations
to adjust the bacterial phenotypes according to the density of bacterial cells. This serves to …

Bacterial quorum sensing: functional features and potential applications in biotechnology

N Mangwani, HR Dash, A Chauhan… - Journal of molecular …, 2012 - karger.com
Quorum sensing (QS) represents an exceptional pattern of cell-to-cell communication in
bacteria using self-synthesized signalling molecules known as autoinducers. Various …