Aspirin protects against acinar cells necrosis in severe acute pancreatitis in mice
G Lu, Z Tong, Y Ding, J Liu, Y Pan… - BioMed Research …, 2016 - Wiley Online Library
Aspirin has a clear anti‐inflammatory effect and is used as an anti‐inflammatory agent for
both acute and long‐term inflammation. Previous study has indicated that aspirin alleviated …
both acute and long‐term inflammation. Previous study has indicated that aspirin alleviated …
Aspirin ameliorates pancreatic inflammation and fibrosis by inhibiting COX-2 expression in experimental chronic pancreatitis
XF Xu, JW Fan, JQ Xin, N Wu, H Gao… - Journal of …, 2022 - Taylor & Francis
Aim Chronic pancreatitis (CP) is a complex and intractable disease mainly manifested as
chronic inflammation and fibrosis. Aspirin (acetylsalicylic acid, ASA) has been reported to be …
chronic inflammation and fibrosis. Aspirin (acetylsalicylic acid, ASA) has been reported to be …
[HTML][HTML] Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis
S Sun, Y Han, C Zhang, H Liu, B Wang… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: Inflammatory disorder and acinar cell death contribute to the initiation and
progression of severe acute pancreatitis (SAP). Adenosine kinase (ADK) has potential …
progression of severe acute pancreatitis (SAP). Adenosine kinase (ADK) has potential …
Artesunate ameliorates severe acute pancreatitis (SAP) in rats by inhibiting expression of pro-inflammatory cytokines and Toll-like receptor 4
Y Cen, C Liu, X Li, Z Yan, M Kuang, Y Su, X Pan… - International …, 2016 - Elsevier
Severe acute pancreatitis (SAP) is a severe clinical condition with significant morbidity and
mortality. Multiple organs dysfunction (MOD) is the leading cause of SAP-related death. The …
mortality. Multiple organs dysfunction (MOD) is the leading cause of SAP-related death. The …
[HTML][HTML] Protective effect of alprostadil on acute pancreatitis in rats via inhibiting janus kinase 2 (JAK2)/STAT3 signal transduction pathway
S Fei, W Li, L Xiang, X Xie, L Zhang - Medical science monitor …, 2019 - ncbi.nlm.nih.gov
Background Alprostadil can inhibit inflammation and reduce inflammation-related injury in
many inflammatory diseases. However, the anti-inflammatory effect of alprostadil in …
many inflammatory diseases. However, the anti-inflammatory effect of alprostadil in …
hP-MSCs attenuate severe acute pancreatitis in mice via inhibiting NLRP3 inflammasome-mediated acinar cell pyroptosis
S Lyu, S Liu, X Guo, Y Zhang, Z Liu, S Shi, W Li, J Pei… - Apoptosis, 2024 - Springer
Background Severe acute pancreatitis (SAP) is a serious gastrointestinal disease that is
facilitated by pancreatic acinar cell death. The protective role of human placental …
facilitated by pancreatic acinar cell death. The protective role of human placental …
Acanthopanax versus 3‐Methyladenine Ameliorates Sodium Taurocholate‐Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats
X Wang, G Zhou, C Liu, R Wei, S Zhu… - Mediators of …, 2016 - Wiley Online Library
Objectives. To observe the therapeutic effects of Acanthopanax and 3‐methyladenine
against severe acute pancreatitis (SAP). Methods. Sodium taurocholate‐induced SAP rats …
against severe acute pancreatitis (SAP). Methods. Sodium taurocholate‐induced SAP rats …
[HTML][HTML] Baicalein protect pancreatic injury in rats with severe acute pancreatitis by inhibiting pro-inflammatory cytokines expression
Abstract Background/Aim Inflammatory cytokines is a key point in the development of
pathogenesis of SAP. Inflammatory mediators TNF-α and IL-6 are up-regulated in serum of …
pathogenesis of SAP. Inflammatory mediators TNF-α and IL-6 are up-regulated in serum of …
Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway
G Tang, C Yu, K Xiang, M Gao, Z Liu, B Yang… - Inflammation …, 2022 - Springer
Background Acute pancreatitis (AP) is an inflammatory process of the pancreas resulting
from biliary obstruction or alcohol consumption. Approximately, 10–20% of AP can evolve …
from biliary obstruction or alcohol consumption. Approximately, 10–20% of AP can evolve …
Macrophages-derived p38α promotes the experimental severe acute pancreatitis by regulating inflammation and autophagy
HN Fan, W Chen, LN Fan, JT Wu, JS Zhu… - International …, 2019 - Elsevier
Background Severe acute pancreatitis (SAP) is a common threat to human health. In the
present study, we aimed to investigate the underlying mechanisms by which p38α in …
present study, we aimed to investigate the underlying mechanisms by which p38α in …