Biotin Homeostasis and Human Disorders: Recent Findings and Perspectives

CE Karachaliou, E Livaniou - International Journal of Molecular Sciences, 2024 - mdpi.com
Biotin (vitamin B7, or vitamin H) is a water-soluble B-vitamin that functions as a cofactor for
carboxylases, ie, enzymes involved in the cellular metabolism of fatty acids and amino acids …

Biotin in metabolism and its relationship to human disease

D Pacheco-Alvarez, RS Solórzano-Vargas… - Archives of medical …, 2002 - Elsevier
Biotin, a water-soluble vitamin, is used as cofactor of enzymes involved in carboxylation
reactions. In humans, there are five biotin-dependent carboxylases: propionyl-CoA …

Biotin

J Zempleni, SSK Wijeratne, YI Hassan - Biofactors, 2009 - Wiley Online Library
Biotin is a water‐soluble vitamin and serves as a coenzyme for five carboxylases in humans.
Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin …

Biotin in metabolism and molecular biology

RJ McMahon - Annual review of nutrition, 2002 - annualreviews.org
▪ Abstract Biotin is a water-soluble vitamin required by all organisms by virtue of its essential
role in carboxylation reactions. Although the metabolism and role of biotin in intermediary …

Biotin

J Zempleni, SSK Wijeratne… - Present knowledge in …, 2012 - Wiley Online Library
Biotin is a water-soluble vitamin and serves as a coenzyme for five carboxylases, which
catalyze key steps in the metabolism of fatty acids, glucose, and amino acids in humans …

Biological effects of pharmacological concentrations of biotin

C Fernandez-Mejia… - Journal of Evidence …, 2011 - journals.sagepub.com
Understanding the molecular mechanisms of vitamins has opened new perspectives
regarding the relationship between nutritional signals and biological functions, which, in …

Molecular genetics of biotin metabolism: old vitamin, new science

RA Gravel, MA Narang - The Journal of nutritional biochemistry, 2005 - Elsevier
Biotin is a water-soluble vitamin that participates as a cofactor in gluconeogenesis, fatty acid
synthesis and branched chain amino acid catabolism. It functions as the carboxyl carrier for …

Biotin: biochemical, physiological and clinical aspects

HM Said - Water soluble vitamins: clinical research and future …, 2012 - Springer
Significant progress has been made in our understanding of the biochemical, physiological
and nutritional aspects of the water-soluble vitamin biotin (vitamin H). It is well know now that …

Biotin

WT Penberthy, M Sadri, J Zempleni - Present Knowledge in Nutrition, 2020 - Elsevier
Biotin is a water-soluble vitamin and serves as a coenzyme for five carboxylases, which
catalyze key steps in the metabolism of fatty acids, glucose, and amino acids …

Biotin in metabolism, gene expression, and human disease

A Leon‐Del‐Rio - Journal of inherited metabolic disease, 2019 - Wiley Online Library
Biotin is a water‐soluble vitamin that belongs to the vitamin B complex and which is an
essential nutrient of all living organisms from bacteria to man. In eukaryotic cells biotin …