[HTML][HTML] Therapeutic miRNA-enriched extracellular vesicles: current approaches and future prospects

J Munir, JK Yoon, S Ryu - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) are 50–300 nm vesicles secreted by eukaryotic cells. They can
carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can …

Exogenous loading of miRNAs into small extracellular vesicles

RC de Abreu, CV Ramos, C Becher… - Journal of …, 2021 - Wiley Online Library
Small extracellular vesicles (sEVs), through their natural ability to interact with biological
membranes and exploit endogenous processing pathways to convey biological information …

[HTML][HTML] Extracellular vesicles: new endogenous shuttles for miRNAs in cancer diagnosis and therapy?

S Martellucci, NS Orefice, A Angelucci, A Luce… - International journal of …, 2020 - mdpi.com
Extracellular Vesicles (EVs) represent a heterogeneous population of membranous cell-
derived structures, including cargo-oriented exosomes and microvesicles. EVs are …

Extracellular vesicle‐based nucleic acid delivery

M Lu, W Shao, H Xing, Y Huang - Interdisciplinary Medicine, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous class of natural vesicles that facilitate
intercellular communication by functional transfer of lipids and biomolecular cargoes, such …

[HTML][HTML] MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells

M Albanese, YFA Chen, C Hüls, K Gärtner… - PLoS …, 2021 - journals.plos.org
Mammalian cells release different types of vesicles, collectively termed extracellular vesicles
(EVs). EVs contain cellular microRNAs (miRNAs) with an apparent potential to deliver their …

[HTML][HTML] The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases

Q Yang, MP Diamond, A Al-Hendy - Journal of clinical epigenetics, 2016 - ncbi.nlm.nih.gov
Cells release into the extracellular environment, diverse types of membrane vesicles of
endosomal and plasma membrane origin called exosomes and microvesicles. A number of …

Achieving the promise of therapeutic extracellular vesicles: the devil is in details of therapeutic loading

DS Sutaria, M Badawi, MA Phelps… - Pharmaceutical …, 2017 - Springer
Extracellular vesicles (EVs) represent a class of cell secreted organelles which naturally
contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular …

Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo

D Zhang, H Lee, Z Zhu… - American Journal of …, 2017 - journals.physiology.org
Exosomes are nanovesicles secreted by cells and contain various molecules including
protein, lipid, and DNA/RNA. They are crucial mediators of the intercellular communication …

[HTML][HTML] Cross-talk between cancer cells and their neighbors via miRNA in extracellular vesicles: an emerging player in cancer metastasis

A Kogure, N Kosaka, T Ochiya - Journal of biomedical science, 2019 - Springer
Cancer metastasis is the major cause of mortality in cancer cases and is responsible for
cancer deaths. It is known that cancer cells communicate with surrounding …

[HTML][HTML] Improved loading of plasma-derived extracellular vesicles to encapsulate antitumor miRNAs

MAC Pomatto, B Bussolati, S D'Antico, S Ghiotto… - … Therapy-Methods & …, 2019 - cell.com
Extracellular vesicles (EVs) carry various molecules involved in intercellular communication
and have raised great interest as drug delivery systems. Several engineering methods have …