[HTML][HTML] Therapeutic miRNA-enriched extracellular vesicles: current approaches and future prospects
Extracellular vesicles (EVs) are 50–300 nm vesicles secreted by eukaryotic cells. They can
carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can …
carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can …
Exogenous loading of miRNAs into small extracellular vesicles
RC de Abreu, CV Ramos, C Becher… - Journal of …, 2021 - Wiley Online Library
Small extracellular vesicles (sEVs), through their natural ability to interact with biological
membranes and exploit endogenous processing pathways to convey biological information …
membranes and exploit endogenous processing pathways to convey biological information …
[HTML][HTML] Extracellular vesicles: new endogenous shuttles for miRNAs in cancer diagnosis and therapy?
Extracellular Vesicles (EVs) represent a heterogeneous population of membranous cell-
derived structures, including cargo-oriented exosomes and microvesicles. EVs are …
derived structures, including cargo-oriented exosomes and microvesicles. EVs are …
Extracellular vesicle‐based nucleic acid delivery
M Lu, W Shao, H Xing, Y Huang - Interdisciplinary Medicine, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous class of natural vesicles that facilitate
intercellular communication by functional transfer of lipids and biomolecular cargoes, such …
intercellular communication by functional transfer of lipids and biomolecular cargoes, such …
[HTML][HTML] MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells
M Albanese, YFA Chen, C Hüls, K Gärtner… - PLoS …, 2021 - journals.plos.org
Mammalian cells release different types of vesicles, collectively termed extracellular vesicles
(EVs). EVs contain cellular microRNAs (miRNAs) with an apparent potential to deliver their …
(EVs). EVs contain cellular microRNAs (miRNAs) with an apparent potential to deliver their …
[HTML][HTML] The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases
Q Yang, MP Diamond, A Al-Hendy - Journal of clinical epigenetics, 2016 - ncbi.nlm.nih.gov
Cells release into the extracellular environment, diverse types of membrane vesicles of
endosomal and plasma membrane origin called exosomes and microvesicles. A number of …
endosomal and plasma membrane origin called exosomes and microvesicles. A number of …
Achieving the promise of therapeutic extracellular vesicles: the devil is in details of therapeutic loading
Extracellular vesicles (EVs) represent a class of cell secreted organelles which naturally
contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular …
contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular …
Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo
Exosomes are nanovesicles secreted by cells and contain various molecules including
protein, lipid, and DNA/RNA. They are crucial mediators of the intercellular communication …
protein, lipid, and DNA/RNA. They are crucial mediators of the intercellular communication …
[HTML][HTML] Cross-talk between cancer cells and their neighbors via miRNA in extracellular vesicles: an emerging player in cancer metastasis
Cancer metastasis is the major cause of mortality in cancer cases and is responsible for
cancer deaths. It is known that cancer cells communicate with surrounding …
cancer deaths. It is known that cancer cells communicate with surrounding …
[HTML][HTML] Improved loading of plasma-derived extracellular vesicles to encapsulate antitumor miRNAs
MAC Pomatto, B Bussolati, S D'Antico, S Ghiotto… - … Therapy-Methods & …, 2019 - cell.com
Extracellular vesicles (EVs) carry various molecules involved in intercellular communication
and have raised great interest as drug delivery systems. Several engineering methods have …
and have raised great interest as drug delivery systems. Several engineering methods have …