The bone marrow side of axial spondyloarthritis

D Mauro, S Gandolfo, E Tirri, G Schett… - Nature Reviews …, 2023 - nature.com
Spondyloarthritis (SpA) is characterized by the infiltration of innate and adaptive immune
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …

Pathogenesis of spondyloarthritis: autoimmune or autoinflammatory?

C Ambarus, N Yeremenko, PP Tak… - Current opinion in …, 2012 - journals.lww.com
Pathogenesis of spondyloarthritis: autoimmune or autoinflamm... : Current Opinion in
Rheumatology Pathogenesis of spondyloarthritis: autoimmune or autoinflammatory …

Novel immune cell phenotypes in spondyloarthritis pathogenesis

D Mauro, D Simone, L Bucci, F Ciccia - Seminars in Immunopathology, 2021 - Springer
Spondyloarthritis (SpA) is a heterogeneous group of chronic inflammatory diseases of
unknown etiology. Over time, the plethora of cellular elements involved in its pathogenesis …

Cytokine “fine tuning” of enthesis tissue homeostasis as a pointer to spondyloarthritis pathogenesis with a focus on relevant TNF and IL-17 targeted therapies

T Russell, C Bridgewood, H Rowe, A Altaie… - Seminars in …, 2021 - Springer
A curious feature of axial disease in ankylosing spondylitis (AS) and related non-
radiographic axial spondyloarthropathy (nrAxSpA) is that spinal inflammation may ultimately …

Progress in spondylarthritis. Immunopathogenesis of spondyloarthritis: which cells drive disease?

L Melis, D Elewaut - Arthritis research & therapy, 2009 - Springer
Spondyloarthritides, or SpA, form a cluster of chronic inflammatory diseases with the axial
skeleton as the most typical disease localisation, although extra-articular manifestations …

Pathophysiology and immunolgical basis of axial spondyloarthritis

MGH van de Sande, D Elewaut - Best Practice & Research Clinical …, 2023 - Elsevier
Over the recent years the wider availability and application of state-of-the-art immunological
technologies greatly advanced the insight into the mechanisms that play an important role in …

New immune cells in spondyloarthritis: key players or innocent bystanders?

K Venken, D Elewaut - Best Practice & Research Clinical Rheumatology, 2015 - Elsevier
The central role of the inflammatory cytokines such as TNF-α, IL-23, and IL-17 in the disease
pathogenesis of spondyloarthritis (SpA) is unquestionable, given the strong efficacy of anti …

Osteoimmunological insights into the pathogenesis of ankylosing spondylitis

L Liu, Y Yuan, S Zhang, J Xu… - Journal of cellular …, 2021 - Wiley Online Library
Ankylosing spondylitis (AS) is inflammatory arthritis predominantly affecting the spine, which
is involved in the disorders of both immune and skeletal systems. The exact pathogenesis of …

Pathophysiology of spondyloarthritis

M Ronneberger, G Schett - Current rheumatology reports, 2011 - Springer
Spondyloarthritis (SpA) is characterized by inflammation and new bone formation in the
spine and entheses. The disease is the result of a complex interplay among susceptibility …

Advances in understanding the pathophysiology of spondyloarthritis

RJ Lories - Best Practice & Research Clinical Rheumatology, 2018 - Elsevier
Progressive understanding of the underlying pathophysiology of axial spondyloarthritis has
successfully translated into innovative therapeutic strategies and successful management of …