Lipodystrophy constitutes a spectrum of diseases characterized by a generalized or partial
absence of adipose tissue. Underscoring the role of healthy fat in maintenance of metabolic …

Lipodystrophies, heterogeneous acquired or inherited disorders characterized by the
selective loss of adipose tissue, predispose affected patients to insulin resistance and its …

Aim Lipodystrophy syndromes are rare heterogeneous disorders characterized by
deficiency of adipose tissue, usually a decrease in leptin levels and, frequently, severe …

A wide range of lipodystrophy syndromes exist, each with varying clinical presentations, and
yet cumulatively they underscore the importance of adipocyte biology in human metabolism …

Lipodystrophies are the result of a range of inherited and acquired causes, but all are
characterized by perturbations in white adipose tissue function and, in many instances, its …

Purpose of review This article focuses on recent progress in understanding the genetics of
lipodystrophy syndromes, the pathophysiology of severe metabolic abnormalities caused by …

Introduction: Lipodystrophy is a heterogeneous group of rare diseases characterized by
various degrees of fat loss which leads to serious morbidity due to metabolic abnormalities …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Aims Lipodystrophy is a rare disorder characterised by abnormal or deficient adipose tissue
formation and distribution. It poses significant challenges to affected individuals, including …

Genetic lipodystrophic syndromes are rare diseases characterized by generalized or partial
fat atrophy (lipoatrophy) associated with severe metabolic complications such as insulin …