Objective Prostate cancer is the second most frequent cancer in men worldwide and kills
over 250,000 men worldwide every year. Prostate cancer is a heterogeneous disease at the …

Goh CL, Schumacher FR, Easton D, Muir K, Henderson B, Kote‐Jarai Z, Eeles RA (The
Institute of Cancer Research, Sutton, Surrey, UK; Keck School of Medicine, University of …

Few genetic risk factors have been demonstrated to be specifically associated with
aggressive prostate cancer (PrCa). Here, we report a case‐case study of PrCa comparing …

Worldwide, familial and epidemiological studies have generated considerable evidence of
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …

Improvements in DNA sequencing technology and discoveries made by large scale genome-
wide association studies have led to enormous insight into the role of genetic variation in …

The inherited link of prostate cancer predisposition has been supported using data from
early epidemiological studies, as well as from familial and twin studies. Early linkage …

Abstract table 2 check and delte For decades, physicians and researchers have recognized
that family history is a significant risk factor for prostate cancer. The identification of the …

Prostate cancer is the most common cancer in men and the second highest cause of cancer-
related mortality in the UK A genetic component in predisposition to prostate cancer has …

Genetic markers and the risk of developing prostate cancer. - Abstract - Europe PMC Sign in |
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BACKGROUND Currently used prognostic markers are limited in their ability to accurately
predict disease progression among patients with localized prostate cancer. We examined 23 …