Pendrin function in airway epithelia

C Nofziger, S Dossena, S Suzuki, K Izuhara… - Cellular Physiology and …, 2011 - karger.com
The expression and function of the anion exchanger pendrin (SLC26A4) was thought to be
limited mainly to the inner ear, kidney and thyroid. Recent data indicates that pendrin is also …

[HTML][HTML] An emerging role of pendrin in health and disease

Y Kumai, D Eladari - Physiological Reports, 2015 - ncbi.nlm.nih.gov
The pendrin gene (SLC26A4) was initially identified through the positional cloning in
patients with Pendred syndrome, a heritable recessive genetic disorder (MIM# 274600) …

Pendrin: physiology, molecular biology and clinical importance

R Grimaldi, P Capuano, N Miranda… - Giornale italiano di …, 2007 - europepmc.org
Pendrin, first identified in 1997, belongs to a superfamily of anion transporters localized in
the thyroid gland, inner ear and kidney. Immunohistochemical studies have shown that …

[引用][C] Iodine: Symporter and oxidation, thyroid hormone biosynthesis

KMD La Perle, SM Jhiang - 2003 - Elsevier

The role of pendrin in iodide regulation

L Fugazzola, N Cerutti, D Mannavola… - Experimental and …, 2001 - thieme-connect.com
Recent advances in human genetics have catalyzed the attention on Pendred's syndrome
and its disease-gene, PDS. Studies on the expression of the PDS gene and on the function …

SLC26A4 expression among autoimmune thyroid tissues

S Belguith-Maalej, SA Rebuffat, I Charfeddine, M Mnif… - Immunobiology, 2011 - Elsevier
CONTEXT: The PDS gene (SLC26A4) is responsible for Pendred syndrome (PS). Genetic
analysis of PDS using Tunisian samples showed evidence for linkage and association with …

DOCA sensitive pendrin expression in kidney, heart, lung and thyroid tissues

L Pelzl, T Pakladok, G Pathare, H Fakhri… - Cellular Physiology and …, 2012 - karger.com
Abstract Background/Aims: Pendrin (SLC26A4), a transporter accomplishing anion
exchange, is expressed in inner ear, thyroid gland, kidneys, lung, liver and heart. Loss or …

Anoctamin-1/TMEM16A is the major apical iodide channel of the thyrocyte. 2

JE Beauwens, LJ Galietta, A Boom, V Kruys - 2014 - journals.physiology.org
Iodide is captured by thyrocytes through the Na+/I-symporter (NIS) before being released
into 20 the follicular lumen, where it is oxidized and incorporated into thyroglobulin for the …

The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland

MF van den Hove, K Croizet-Berger, F Jouret… - …, 2006 - academic.oup.com
Genetic inactivation of ClC-5, a voltage-gated chloride channel prominently expressed in the
kidney, leads to proteinuria because of defective apical endocytosis in proximal tubular …

[PDF][PDF] The saliva/serum iodide ratio as an index of sodium/iodide symporter efficiency

GE Abraham, D Brownstein, JD Flechas - The Original Internist, 2005 - refp.cohlife.org
The essential element iodine is present in every organ and tissue of the human body, not
just the thyroid gland. 1 Several cells beside the thyrocyte concentrate peripheral iodide …