While there is considerable evidence about sex-related differences between men and
women in drug metabolism, efficacy and safety of frequently prescribed drugs such as …

In recent years, it has become clear that women and men may differ for drug response. Also,
there is an increasing recognition on the role of sex hormones on pharmacokinetics and …

The influence of biological sex on pharmacokinetics and pharmacodynamics has been
previously described for each step of the metabolic cascade of pharmaceuticals. Women …

Significant differences that exist between the sexes affect the prevalence, incidence and
severity of a broad range of diseases and conditions. Men and women also differ in their …

Background Women experience adverse drug reactions, ADRs, nearly twice as often as
men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood …

Gender-related differences in pharmacokinetics have frequently been considered as
potentially important determinants for the clinical effectiveness of drug therapy. The …

In this review I have attempted to summarize gender differences in pharmacokinetics
involving the cytochrome P450 (CYP) isozymes of young and mature adults, excluding the …

Pharmacological response depends on multiple factors and one of them is sex–gender.
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …

Cardiovascular disease (CVD) is the leading cause of mortality worldwide in both sexes.
Despite considerable progress in better understanding the patterns of disease in women …

Background Evidence from clinical research indicates that men and women can differ in
response to drug treatment. The knowledge database Janusmed Sex and Gender was …