Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health
concern. In this study, we conducted a whole-genome-based molecular characterization to …

Pseudomonas aeruginosa is an opportunistic pathogen responsible for ventilator-acquired
pneumonia, acute lower respiratory tract infections in immunocompromised patients and …

Background Pseudomonas aeruginosa is ubiquitous, has intrinsic antibiotic resistance
mechanisms, and is associated with serious hospital-associated infections. It has evolved …

Accurate typing methods are required for efficient infection control. The emergence of whole-
genome sequencing (WGS) technologies has enabled the development of genome-based …

Extensive use of next-generation sequencing (NGS) for pathogen profiling has the potential
to transform our understanding of how genomic plasticity contributes to phenotypic …

Objectives This study aimed to identify the multiple drug resistance mechanisms and various
virulence genes in high-level carbapenem-resistant Pseudomonas aeruginosa (CARPA) …

Background Multidrug resistance has become a quandary in the treatment of bacterial
infections. The effect of resistance mutations and the fitness cost on the pathogenicity of …

Over the past century, Pseudomonas aeruginosa has become an increasingly important
pathogen, particularly in individuals with cystic fibrosis and in intensive care units worldwide …

Pseudomonas aeruginosa is a ubiquitous microorganism and an important opportunistic
pathogen responsible for a broad spectrum of infections mainly in immunosuppressed and …