This randomized, placebo-controlled, double-masked, parallel-group trial assessed the
serum cholesterol—lowering effects of atorvastatin, a new 3-hydroxy-3-methylglutaryl …

The 6-week efficacy and safety of atorvastatin versus simvastatin was determined during a
54-week, open-label, multicenter, parallel-arm, treat-to-target study. In all, 1,424 patients …

Background and objective Despite the favorable effects of reduction of low-density
lipoprotein-cholesterol (LDL-C) levels in decreasing the risk of coronary heart disease, many …

Background: Atorvastatin is a synthetic inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase. In placebo-controlled trials, it has been shown to achieve significant …

OBJECTIVE: To review the efficacy and safety of atorvastatin in the treatment of
dyslipidemias. DATA SOURCES: A MEDLINE search (January 1960–April 1998), Current …

Background: Simvastatin and atorvastatin are effective statins for treating
hypercholesterolemia. Hypothesis: The study was undertaken to compare the efficacy and …

Background: Atorvastatin, a new enantiomerically pure synthetic statin, has shown a marked
low-density lipoprotein (LDL) cholesterol reduction at doses ranging from 10 to 80 mg/d …

Background & Objectives The aim of this study was to investigate the efficacy & safety of a
new HMG-CoA reductase inhibitor, atorvastatin, to improve serum lipid profiles in patients …

Combined hyperlipidemia is associated with endothelial dysfunction. Atorvastatin has lipid-
lowering and pleiotropic properties, including a protective effect on endothelial function. This …

The effect of high-dose atorvastatin treatment in normocholesterolemic patients was studied
to answer the following questions: Is there a detectable benefit on endothelial function and …