Mesenchymal stem/stromal cells (MSCs) are multipotent progenitor cells of mesodermal
origin. Due to their capacity for self‐renewal and differentiation into several cell types, MSCs …

Chronic pain is a common condition that seriously affects the quality of human life with
variable etiology and complicated symptoms; people who suffer from chronic pain may …

MSCs were firstly described around 1970s by Friedenstein and his collaborators as a
subpopulation of colony forming, clonogenic, plastic adherent stromal bone marrow derived …

The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …

Musculoskeletal disorders are one of the biggest contributors to morbidity and place an
enormous burden on the health care system in an aging population. Owing to their …

Over the past two decades, mesenchymal stromal cells (MSCs) have demonstrated great
potential in the treatment of inflammation-related conditions. Numerous early stage clinical …

ABSTRACT BACKGROUND CONTEXT Mesenchymal stem cells (MSCs) secretome or
conditioned medium (CM) is a complex cocktail of different molecules, some of which …

Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …

Small extracellular vesicles (sEVs) have been identified as a noteworthy paracrine
mechanism of intercellular communication in diagnosing and managing neurological …

Though there are various etiologies to chronic pain, one common feature is that painful
states are associated with increased inflammation. This is verified by studies in both animal …