Treatable traits that predict health status and treatment response in airway disease

SA Hiles, PG Gibson, A Agusti, VM McDonald - The Journal of Allergy and …, 2021 - Elsevier
Background A strategy based on the assessment and management of treatable traits (TTs)
has been proposed as a new paradigm in airway disease. There is a potentially long list of …

Effectiveness of interventions targeting treatable traits for the management of obstructive airway diseases: a systematic review and meta-analysis

MR Sarwar, VM McDonald, MJ Abramson… - The Journal of Allergy …, 2022 - Elsevier
Background The management of obstructive airway diseases (OADs) is complex. The
treatable traits (TTs) approach may be an effective strategy for managing OADs. Objective …

Treatable traits in airway disease: from theory to practice

A Agusti, PG Gibson, VM McDonald - The Journal of Allergy and Clinical …, 2023 - Elsevier
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are
prevalent and complex conditions that often coexist in the same patient. To address this …

Treatable traits in the NOVELTY study

A Agustí, E Rapsomaniki, R Beasley, R Hughes… - …, 2022 - Wiley Online Library
Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …

Targeting treatable traits in severe asthma: a randomised controlled trial

VM McDonald, VL Clark… - European …, 2020 - Eur Respiratory Soc
Rationale Treatable traits have been proposed as a new paradigm for airway disease
management. Objectives To characterise treatable traits in a severe asthma population and …

[HTML][HTML] Should we apply a treatable traits approach to asthma care?

J Melhorn, I Howell, ID Pavord - Annals of Allergy, Asthma & Immunology, 2022 - Elsevier
Objective To explore the evidence for adopting a “treatable traits” approach to asthma
management. Data Sources PubMed, Medline, and Google Scholar. Study Selections The …

[HTML][HTML] Moving towards a treatable traits model of care for the management of obstructive airways diseases

A Agusti, N Barnes, AA Cruz, PG Gibson, LG Heaney… - Respiratory …, 2021 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airways diseases. Both are complex and heterogeneous. Traditionally, clinical guidelines …

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report

VM McDonald, J Fingleton, A Agusti… - European …, 2019 - Eur Respiratory Soc
“Treatable traits” have been proposed as a new paradigm for the management of airway
diseases, particularly complex disease, which aims to apply personalised medicine to each …

[HTML][HTML] Treatable traits in an English cohort: prevalence and predictors of future decline in lung function and quality of life in COPD

MR Sarwar, VM McDonald, MJ Abramson… - ERJ open …, 2021 - Eur Respiratory Soc
Background “Treatable traits (TTs)” is a precision medicine approach for facilitating
multidimensional assessment of every patient with chronic airway disease, in order to …

Treatable traits in asthma and COPD

VM McDonald, PG Gibson - Archivos de Bronconeumología, 2022 - Elsevier
Treatable Traits personalises the management of airway diseases. 1, 2 This model of care
packages assessment of measurable, modifiable, and clinically relevant phenotypes, and …