Increased plasma non-esterified fatty acids (NEFAs) link obesity with insulin resistance and
type 2 diabetes mellitus (T2DM). However, in contrast to the saturated FA (SFA) palmitic …

The widespread acceptance that increased dietary n-3 polyunsaturated fatty acids (PUFAs),
especially α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid …

Epidemiological, human, animal, and cell culture studies show that n− 3 fatty acids,
especially α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid …

Linoleic acid is the most prominent polyunsaturated fatty acid (PUFA) in the Western diet. It
is virtually found in every food we eat and is the predominant PUFA in land-based meats …

Cardiovascular disease (CVD) is the leading cause of death worldwide. Risk factors for
developing this disease include high serum concentrations of total cholesterol, triglycerides …

The intake of linoleic acid (LA) has increased dramatically in the standard American diet. LA
is generally promoted as supporting human health, but there exists controversy regarding …

Linoleic acid (LA) is a bioactive fatty acid with diverse effects on human physiology and
pathophysiology. LA is a major dietary fatty acid, and also one of the most abundant fatty …

It is now recognized that the amount and type of dietary fat consumed play an important role
in metabolic health. In humans, high intake of polyunsaturated fatty acids (PUFAs) has been …

Background: Experimental evidence suggests that hepatic de novo lipogenesis (DNL)
affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and …

Background: Polyunsaturated fats (PUFAs) have been shown to reduce type 2 diabetes
(T2DM) risk and improve insulin responsiveness in T2DM subjects, but whether the plant …