Wallerian degeneration, the progressive disintegration of distal axons and myelin that
occurs after peripheral nerve injury, is essential for creating a permissive microenvironment …

Disturbance in the neuronal network leads to instability in the microtubule (MT) railroad of
axons, causing hindrance in the intra-axonal transport and making it difficult to re-establish …

Axons in the CNS do not regrow after injury, whereas lesioned axons in the peripheral
nervous system (PNS) regenerate. Lesioned CNS axons form characteristic swellings at …

Wallerian degeneration occurs immediately following injury to mammal peripheral nerves.
To better understand the molecular events occurring during Wallerian degeneration, a rat …

Traumatic CNS injuries often cause permanent, devastating disabilities due to a lack of
regeneration of damaged axons. Next to an insufficient intrinsic capability of CNS neurons to …

Most neurons must last a lifetime and their microtubule cytoskeleton is an important
contributor to their longevity. Neurons have some of the most stable microtubules of all cells …

Wallerian degeneration is a subject of major interest in neuroscience. A large number of
genes are differentially regulated during the distinct stages of Wallerian degeneration …

Wallerian degeneration (WD) remains a subject of critical research interest in modern
neurobiology. WD is a process which a large number of genes are differentially regulated …

Wallerian degeneration (WD) remains an important research topic. Many genes are
differentially expressed during the process of WD, but the precise mechanisms responsible …

During the development of the nervous system and regeneration following injury,
microtubules (MTs) are required for neurite elongation. Whether this elongation occurs …