Vertebrate toll-like receptors (TLRs) sense invading pathogens by recognizing bacterial and
viral structures and, as a result, activate innate and adaptive immune responses. Ten human …

Toll-like receptors (TLRs) are part of the innate immune system, and they belong to the
pattern recognition receptors (PRR) family. The PRR family is designed to recognize and …

Toll-like receptor 9 (TLR9) agonists have demonstrated substantial potential as vaccine
adjuvants, and as mono-or combination therapies for the treatment of cancer and infectious …

Oligodeoxyribonucleotides containing unmethylated CpG motifs act as TLR9 agonists. In
this study, we evaluated oligonucleotides containing an unmethylated CpG motif in which …

CpG oligodeoxynucleotides (ODN) activate the immune system and are promising
immunotherapeutic agents against infectious diseases, allergy/asthma and cancer. It has …

The innate immune system detects pathogens by the presence of highly conserved
pathogen-expressed molecules, which trigger host immune defenses. Toll-like receptor …

Oligodeoxynucleotides (ODNs) containing unmethylated CpG dinucleotides act as agonists
of TLR9 and induce Th1-type immune responses. In the present study, we synthesized CpG …

Oligodeoxynucleotides (ODNs) with unmethylated deoxycytosine-deoxyguanosine (CpG)
motifs are recognised by Toll-like receptor (TLR) 9 expressed in s-pecialised cell subsets of …

In vertebrates, the TLRs are a family of specialized immune receptors that induce protective
immune responses when they detect highly conserved pathogen-expressed molecules …

Toll like receptors (TLRs) are transmembrane glycoproteins that recognize conserved
microbial molecules. Engagement of TLRs activates innate and adaptive immunity. TLR …