Animal models of HIV infection have played an important role in the development of
antiretroviral drugs. Although each animal model has its limitations and never completely …

Several nonhuman primate models are used in HIV and AIDS research. In contrast to HIV-1
infection of chimpanzees, infection of macaque species with simian immunodeficiency virus …

Several nonhuman primate models are used in HIV/AIDS research. In contrast to natural
host models, infection of macaques with virulent simian immunodeficiency virus (SIV) …

The AIDS pandemic continues to present us with unique scientific and public health
challenges. Although the development of effective antiretroviral therapy has been a major …

Despite decades of intensive basic and clinical research efforts, there is still no successful
vaccine candidate against human immunodeficiency virus (HIV-1). Standard combined …

In this review, we describe the most recent advances in the use of animal models for
HIV/AIDS research, and will break down these advances in three areas: models for virus …

The development of a predictive, small animal model for human immunodeficiency virus
type 1 (HIV-1) disease would greatly facilitate the analysis of many aspects of viral infection …

Historically, animal model systems have been important components of biomedical
research, and the same is proving true for research directed at the human immunodeficiency …

AIDS is among the most devastating diseases of our time, claiming the lives of
approximately 3 million people per year. The primary cause of AIDS, human …

Current HIV therapy is not curative regardless of how soon after infection it is initiated or how
long it is administered, and therapy interruption almost invariably results in robust viral …