Lysine methylation is well-documented and relatively well-understood with respect to
histone modification and the epigenetic regulation of gene expression. Enzymes called …

Lysine methylation, catalyzed by protein lysine methyltransferases (PKMTs), is a central post-
translational modification regulating many signaling pathways. It has direct and indirect …

Proteins are regulated by an incredible array of posttranslational modifications (PTMs).
Methylation of lysine residues on histone proteins is a PTM with well-established roles in …

Lysine methylation is a common posttranslational modification (PTM) of histones that is
important for the epigenetic regulation of transcription and chromatin in eukaryotes …

Protein lysine methylation is a distinct posttranslational modification that causes minimal
changes in the size and electrostatic status of lysine residues. Lysine methylation plays …

Lysine methylation is a prevalent post-translational modification (PTM) used by the cell to
reversibly regulate protein function. Although it has been extensively studied in the context …

A robust signaling network is essential for cell survival. At the molecular level, this is often
mediated by as many as 200 different types of post‐translational modifications (PTMs) that …

The process of post-translational covalent modification of proteins represents a transcription-
independent regulatory mechanism allowing rapid alteration of protein activity and function …

Protein lysine methylation is a functionally diverse post-translational modification involved in
various major cellular processes. Lysine methylation can modulate proteins activity, stability …

Histone lysine methylation has emerged as a critical player in the regulation of gene
expression, cell cycle, genome stability, and nuclear architecture. Over the past decade, a …