Background Some patients with asthma have frequent exacerbations and persistent airflow
obstruction despite treatment with inhaled glucocorticoids and long-acting beta-agonists …

Anticholinergic agents have been available for the treatment of airways obstruction for many
decades. For patients with chronic obstructive pulmonary disease (COPD), many …

The duration of bronchoprotection against methacholine-induced bronchoconstriction by
long-acting muscarinic antagonists (LAMA's) in asthmatics and whether these drugs differ in …

OBJECTIVE To review clinical data on the use of the long-acting anticholinergic agent
tiotropium in patients with asthma. DATA SOURCES A literature search was performed via …

Inhaled corticosteroids (ICS) are effective in the majority of children with asthma and are
considered the mainstay of therapy. However, for those children who have inadequate …

Tiotropium is a long-acting inhaled antimuscarinic bronchodilator that has recently received
marketing authorization for the indication of asthma with dose delivery via the Respimat® …

Long‐acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the
same dose of ICS alone for adults with asthma - Anderson, DE - 2015 | Cochrane Library Skip …

Acetlycholine is involved in the control of airway smooth muscle constriction and in
recruitment of inflammatory cells via neuronal and paracrine effects on muscarinic type 3 …

Background Tiotropium bromide (TIO) is a long-acting muscarinic antagonist recommended
as an add-on therapy option for patients with uncontrolled asthma on inhaled corticosteroids …

Background Adding tiotropium to existing inhaled corticosteroid (ICS) maintenance therapy
with or without a long-acting β 2-agonist (LABA) has been shown to be beneficial in patients …