Computational predictions of aerosol transport and deposition in the human respiratory tract
can assist in evaluating detrimental or therapeutic health effects when inhaling toxic …

Prediction of the air-particle dynamics in human lungs can reveal critical deposition sites of
toxins or can determine best physical parameters for direct drug delivery and associated …

Little is known about transport throughout the respiration cycle in the conducting airways. It
is challenging to appropriately describe the time‐dependent number of particles entering …

In silico models of airflow and particle deposition in the lungs are increasingly used to
determine the therapeutic or toxic effects of inhaled aerosols. While computational methods …

We simulate two-and three-dimensional (2D and 3D) aerosol transport for different particle
diameters within alveolated ducts. In agreement with previous studies (WJ Federspiel and JJ …

One-dimensional transport models (trumpet model and multibranch-point model) derived
from those developed to study gas transport and mixing in the lung are used to simulate …

Pulmonary drug delivery is becoming a favored route for administering drugs to treat both
lung and systemic diseases. Examples of lung diseases include asthma, cystic fibrosis and …

Computer simulations of airflow and particle-transport phenomena within the human
respiratory system have important applications to aerosol therapy (eg, the targeted delivery …

The study of particle transport and deposition in the human lung is critical in health risk
assessment of air pollutants and in pharmaceutical drug delivery. Several computational …

Quantitative data on aerosol deposition in the human respiratory tract are useful for
understanding the causes of certain lung diseases and for designing efficient drug delivery …