Several acridine derivatives have been screened for their therapeutic potential and some
are already established as antiprotozoan, antibacterial or anticancer agents. However …

Lung cancer is still the leading cause of cancer-related death worldwide, indicating a
necessity to develop more effective therapy. Acridine derivatives are potential anticancer …

Lung cancer is not only the most commonly diagnosed cancers worldwide but it is still the
leading cause of cancer-related death. Acridine derivatives are a class of anticancer agents …

Background Acridine compounds have been described as promising anticancer agents.
Previous studies showed that (E)-1'-((4-chlorobenzylidene) amino)-5'-oxo-1', 5'-dihydro-10H …

A series of nine tetrahydroacridine derivatives with iodobenzoic moiety were synthesized
and evaluated for their cytotoxic activity against cancer cell lines—A549 (human lung …

During the last 4 decades, intensive research has focussed on the effect of small organic
molecules with antitumour activity that are able to intercalate into DNA and inhibit …

Acridine is a heterocyclic nucleus consisting of three fused rings heterocyclic moiety and a
presence of Nitrogen in the ring structure. It is used in a large number of therapeutically …

Acridine derivatives are one of the oldest classes of bioactives, widely used as antibacterial
and antiprotozoal agents. Some work in these areas continues, but recent research has …

Acridine derivatives show a broad range of biological activities. They have primarily been
explored as chemotherapeutic agents (anticancer, antibacterial, antiprotozoal), because of …

This review summarized the current breakthroughs in the chemistry of acridines as anti-
cancer agents, including new structural and biologically active acridine attributes. Acridine …