[HTML][HTML] Cardiovascular disease, mortality, and magnesium in chronic kidney disease: growing interest in magnesium-related interventions

R Ikee - Renal Replacement Therapy, 2018 - Springer
Magnesium (Mg) is an essential element that plays pivotal roles in a number of biological
processes in the human body. Hypomagnesemia is involved in the pathophysiology of …

The effect of increasing dialysate magnesium on serum calcification propensity in subjects with end stage kidney disease: a randomized, controlled clinical trial

I Bressendorff, D Hansen, M Schou… - Clinical Journal of the …, 2018 - journals.lww.com
Results Fifty-nine subjects were enrolled in the trial, and of these, 57 completed the
intervention and were analyzed for the primary outcome. In the standard dialysate …

Getting the balance right: assessing causes and extent of vascular calcification in chronic kidney disease

M Ketteler, PH Biggar - Nephrology, 2009 - Wiley Online Library
Vascular calcification is part of the definition of chronic kidney disease–mineral and bone
disorder (CKD‐MBD). It is also a surrogate parameter of cardiovascular and all‐cause …

Vitamin K for the treatment of cardiovascular disease in End-Stage Renal Disease patients: Is there hope?

S Roumeliotis, A Roumeliotis… - Current Vascular …, 2021 - ingentaconnect.com
In Chronic Kidney Disease, vascular calcification (VC) is highly prevalent even at early
stages and is gradually enhanced, along with disease progression to End-Stage Renal …

Inhibit progression of coronary artery calcification with vitamin K in hemodialysis patients (the iPACK-HD study): a randomized, placebo-controlled multi-center, pilot …

RM Holden, SL Booth, D Zimmerman… - Nephrology Dialysis …, 2023 - academic.oup.com
Background Vitamin K activates matrix Gla protein (MGP), a key inhibitor of vascular
calcification. There is a high prevalence of sub-clinical vitamin K deficiency in patients with …

Magnesium in chronic kidney disease: challenges and opportunities

M Kanbay, D Goldsmith, ME Uyar, F Turgut, A Covic - Blood purification, 2010 - karger.com
Cardiovascular disease is the leading cause of mortality and morbidity in patients with
chronic kidney disease, which is partly explained by the fact that 40–70% of patients …

[HTML][HTML] Diurnal variation of magnesium and the mineral metabolism in patients with chronic kidney disease

AS Møller, I Bressendorff, A Nordholm, S Egstrand… - Bone Reports, 2021 - Elsevier
Increasing levels of magnesium in blood are associated with reduced risk of cardiovascular
disease in chronic kidney disease (CKD). Magnesium supplementation may reduce the …

[HTML][HTML] Serum magnesium is inversely associated with coronary artery calcification in the Genetics of Atherosclerotic Disease (GEA) study

R Posadas-Sánchez, C Posadas-Romero… - Nutrition journal, 2015 - Springer
Background Serum magnesium is inversely associated to coronary artery calcification (CAC)
in patients with chronic kidney disease. There is little information on this association in a …

Vitamin K1 and progression of cardiovascular calcifications in hemodialysis patients: the VitaVasK randomized controlled trial

T Saritas, S Reinartz, T Krüger, M Ketteler… - Clinical kidney …, 2022 - academic.oup.com
Background Cardiovascular calcifications are prevented by matrix Gla protein (MGP), a
vitamin K–dependent protein. Haemodialysis patients exhibit marked vitamin K deficiency …

[HTML][HTML] Vitamin K supplementation for prevention of vascular calcification in chronic kidney disease patients: are we there yet?

S Roumeliotis, A Duni, V Vaios, A Kitsos… - Nutrients, 2022 - mdpi.com
Chronic Kidney Disease (CKD) patients are at high risk of presenting with arterial
calcification or stiffness, which confers increased cardiovascular mortality and morbidity. In …