A totally effective, antimalarial vaccine must involve sporozoite and merozoite proteins (or
their fragments) to ensure complete parasite blocking during critical invasion stages. This …

Biochemical, structural and single amino acid level analysis of 49 Plasmodium falciparum
protein regions (13 sporozoite and 36 merozoite proteins) has highlighted the functional role …

Plasmodium falciparum causes the most lethal form of malaria in humans and is responsible
for over two million deaths per year. The development of a vaccine against this parasite is an …

Plasmodium falciparum multi-stage proteins are involved in vital processes for parasite
survival, which turns them into attractive targets for studies aimed at developing a fully …

Conserved Plasmodium falciparum merozoite high activity binding peptides (HABPs)
involved in red blood cell (RBC) invasion which are present in merozoite surface proteins …

Plasmodium falciparum erythrocyte invasion is a multistep process that involves a spectrum
of interactions that are not well characterized. We have characterized a 113-kDa …

Malaria is a disease caused by parasites of Plasmodium species. It is responsible for around
1-2 million deaths annually, mainly children under the age of 5. It occurs mainly in tropical …

Despite significant global efforts, a completely effective vaccine against Plasmodium
falciparum, the species responsible for the most serious form of malaria, has not been yet …

All the symptoms and pathology of malaria are caused by the intraerythrocytic stages of the
Plasmodium parasite life cycle. Because Plasmodium parasites cannot replicate outside a …

The Plasmodium falciparum sporozoite infects different types of cells in a mosquito's salivary
glands and human epithelial and Kuppfer cells and hepatocytes. These become …