[HTML][HTML] Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

S Deb, SQ Wong, J Li, H Do, J Weiss, D Byrne… - British journal of …, 2014 - nature.com
Background: Male breast cancer (MBC) is still poorly understood with a large proportion
arising in families with a history of breast cancer. Genomic studies have focused on germline …

[HTML][HTML] Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated …

S Deb, N Jene, CF investigators, SB Fox - BMC cancer, 2012 - Springer
Background Male breast cancer (MBC) is an uncommon and relatively uncharacterised
disease accounting for< 1% of all breast cancers. A significant proportion occurs in families …

[HTML][HTML] Male breast cancer: results of the application of multigene panel testing to an Italian cohort of patients

G Tedaldi, M Tebaldi, V Zampiga, I Cangini, F Pirini… - Diagnostics, 2020 - mdpi.com
Male breast cancer (MBC) is a rare tumor, accounting for less than 1% of all breast cancers.
In MBC, genetic predisposition plays an important role; however, only a few studies have …

Germline deleterious mutations in genes other than BRCA2 are infrequent in male breast cancer

F Fostira, E Saloustros, P Apostolou, A Vagena… - Breast Cancer Research …, 2018 - Springer
Purpose Male breast cancer (MBC) is a rare cancer entity, with mutations in BRCA1 and
BRCA2 genes accounting for~ 10% of patients. Multiple-gene sequencing has already …

[HTML][HTML] Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results

M Pritzlaff, P Summerour, R McFarland, S Li… - Breast cancer research …, 2017 - Springer
Purpose Genetic predisposition to male breast cancer (MBC) is not well understood. The
aim of this study was to better define the predisposition genes contributing to MBC and the …

The cancer genetics and pathology of male breast cancer

S Deb, SR Lakhani, L Ottini, SB Fox - Histopathology, 2016 - Wiley Online Library
Male breast cancer (MBC) is an uncommon and poorly understood disease. Recent
molecular studies have shown important differences from female breast cancer which are …

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy

P Rizzolo, V Zelli, V Silvestri, V Valentini… - … Journal of Cancer, 2019 - Wiley Online Library
Breast cancer (BC) in men is rare and genetic predisposition is likely to play a relevant role
in its etiology. Inherited mutations in BRCA1/2 account for about 13% of all cases and …

[HTML][HTML] Male breast cancer: from molecular genetics to clinical management

M Pensabene, C Von Arx, M De Laurentiis - Cancers, 2022 - mdpi.com
Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …

[HTML][HTML] Transcriptome of male breast cancer matched with germline profiling reveals novel molecular subtypes with possible clinical relevance

V Zelli, V Silvestri, V Valentini, A Bucalo, P Rizzolo… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer in men is a rare disease; however, morbidity and mortality in
male breast cancer (MBC) patients is a serious concern. The identification of specific …

The genomic landscape of male breast cancers

S Piscuoglio, CKY Ng, MP Murray… - Clinical Cancer …, 2016 - AACR
Purpose: Male breast cancer is rare, and its genomic landscape has yet to be fully
characterized. Lacking studies in men, treatment of males with breast cancer is extrapolated …