[HTML][HTML] Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations
Background: Male breast cancer (MBC) is still poorly understood with a large proportion
arising in families with a history of breast cancer. Genomic studies have focused on germline …
arising in families with a history of breast cancer. Genomic studies have focused on germline …
[HTML][HTML] Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated …
S Deb, N Jene, CF investigators, SB Fox - BMC cancer, 2012 - Springer
Background Male breast cancer (MBC) is an uncommon and relatively uncharacterised
disease accounting for< 1% of all breast cancers. A significant proportion occurs in families …
disease accounting for< 1% of all breast cancers. A significant proportion occurs in families …
[HTML][HTML] Male breast cancer: results of the application of multigene panel testing to an Italian cohort of patients
Male breast cancer (MBC) is a rare tumor, accounting for less than 1% of all breast cancers.
In MBC, genetic predisposition plays an important role; however, only a few studies have …
In MBC, genetic predisposition plays an important role; however, only a few studies have …
Germline deleterious mutations in genes other than BRCA2 are infrequent in male breast cancer
F Fostira, E Saloustros, P Apostolou, A Vagena… - Breast Cancer Research …, 2018 - Springer
Purpose Male breast cancer (MBC) is a rare cancer entity, with mutations in BRCA1 and
BRCA2 genes accounting for~ 10% of patients. Multiple-gene sequencing has already …
BRCA2 genes accounting for~ 10% of patients. Multiple-gene sequencing has already …
[HTML][HTML] Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results
M Pritzlaff, P Summerour, R McFarland, S Li… - Breast cancer research …, 2017 - Springer
Purpose Genetic predisposition to male breast cancer (MBC) is not well understood. The
aim of this study was to better define the predisposition genes contributing to MBC and the …
aim of this study was to better define the predisposition genes contributing to MBC and the …
The cancer genetics and pathology of male breast cancer
Male breast cancer (MBC) is an uncommon and poorly understood disease. Recent
molecular studies have shown important differences from female breast cancer which are …
molecular studies have shown important differences from female breast cancer which are …
Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy
P Rizzolo, V Zelli, V Silvestri, V Valentini… - … Journal of Cancer, 2019 - Wiley Online Library
Breast cancer (BC) in men is rare and genetic predisposition is likely to play a relevant role
in its etiology. Inherited mutations in BRCA1/2 account for about 13% of all cases and …
in its etiology. Inherited mutations in BRCA1/2 account for about 13% of all cases and …
[HTML][HTML] Male breast cancer: from molecular genetics to clinical management
M Pensabene, C Von Arx, M De Laurentiis - Cancers, 2022 - mdpi.com
Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
[HTML][HTML] Transcriptome of male breast cancer matched with germline profiling reveals novel molecular subtypes with possible clinical relevance
V Zelli, V Silvestri, V Valentini, A Bucalo, P Rizzolo… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer in men is a rare disease; however, morbidity and mortality in
male breast cancer (MBC) patients is a serious concern. The identification of specific …
male breast cancer (MBC) patients is a serious concern. The identification of specific …
The genomic landscape of male breast cancers
Purpose: Male breast cancer is rare, and its genomic landscape has yet to be fully
characterized. Lacking studies in men, treatment of males with breast cancer is extrapolated …
characterized. Lacking studies in men, treatment of males with breast cancer is extrapolated …