[PDF][PDF] Randomized controlled trials do not reflect reality: real-world analyses are critical for treatment guidelines!

MTR Grapow, R von Wattenwyl, U Guller… - The Journal of thoracic …, 2006 - core.ac.uk
Arecent article by Hannan and coworkers 1 including almost 60,000 patients from New
York's cardiac registries forces us to reflect on the reliability of inferences made from …

Randomized clinical trials for new surgical operations: square peg in a round hole?

JD Cooper - The Journal of Thoracic and Cardiovascular Surgery, 2010 - jtcvs.org
In 1995, Time magazine published an article entitled ''Are Surgeons Too Creative?''that
examined the question of whether new operations should be regulated. The public and …

The American Association for Thoracic Surgery and the Society of Thoracic Surgeons reasoning for not endorsing the 2021 ACC/AHA/SCAI coronary revascularization …

JF Sabik, FG Bakaeen, M Ruel, MR Moon… - The Journal of Thoracic …, 2022 - jtcvs.org
The American Association for Thoracic Surgery (AATS) and The Society of Thoracic
Surgeons (STS) have decided not to endorse the 2021 American College of …

Surgical research revisited: clinical trials in the cardiothoracic surgical literature

AC Anyanwu, T Treasure - European journal of cardio-thoracic …, 2004 - academic.oup.com
Objective: Surgeons have been criticised for not undertaking high-quality research. This
study examines the quality of randomised controlled trials (RCTs) in the cardiothoracic …

The Cardiothoracic Surgery Network: randomized clinical trials in the operating room

TJ Gardner, PT O'Gara - The Journal of thoracic and cardiovascular surgery, 2010 - jtcvs.org
In 2006, the National Heart, Lung, and Blood Institute (NHLBI) announced the formation of a
new clinical research network titled,''The Network for Cardiothoracic Surgical Investigations …

Innovation and comparative-effectiveness research in cardiac surgery

ED Peterson - New England Journal of Medicine, 2009 - Mass Medical Soc
Cardiac surgery has always been a unique combination of art and science. The field is
advanced by those who push the envelope by suggesting innovations. Yet promising …

Randomized trials, observational studies, and the illusive search for the source of truth

M Gaudino, E Bagiella, HL Chang… - The Journal of Thoracic …, 2022 - jtcvs.org
Obesity has been artfully described as starvation in a sea of calories. Applying similar logic,
one might conclude that the age of information has left us desperately seeking truth in a …

Five years after the SYNTAX trial: what have we learnt?

P Davierwala, FW Mohr - European Journal of Cardio-Thoracic …, 2013 - academic.oup.com
Ever since the advent of percutaneous intervention (PCI) for the treatment of coronary artery
disease (CAD), the optimal choice of therapy (PCI or coronary artery bypass grafting …

[PDF][PDF] 'Cherry-picking'patients for randomized, controlled trials-reliving the past

V Farooq, PW Serruys - J Am Coll Cardiol, 2013 - core.ac.uk
We read with interest the VA CARDS (Veterans Affairs Coronary Artery Revascularization in
Diabetes) study (1) comparing percutaneous coronary intervention (PCI) and coronary artery …

Methodological standards for the design, implementation, and analysis of randomized trials in cardiac surgery: a scientific statement from the American Heart …

M Gaudino, J Chikwe, E Bagiella, DL Bhatt, T Doenst… - Circulation, 2022 - Am Heart Assoc
Cardiac surgery presents specific methodological challenges in the design, implementation,
and analysis of randomized controlled trials. The purposes of this scientific statement are to …