A survey on “Trojan Horse” peptides: opportunities, issues and controlled entry to “Troy”

NQ Shi, XR Qi, B Xiang, Y Zhang - Journal of controlled release, 2014 - Elsevier
Abstract Cell-penetrating peptides (CPPs), often vividly termed as the “Trojan Horse”
peptides, have attracted considerable interest for the intracellular delivery of a wide range of …

Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules

SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

A novel cell-penetrating peptide, M918, for efficient delivery of proteins and peptide nucleic acids

S El-Andaloussi, HJ Johansson, T Holm, Ü Langel - Molecular Therapy, 2007 - cell.com
Cell-penetrating peptides (CPPs) have attracted increasing attention in the past decade as a
result of their high potential to convey various, otherwise impermeable, bioactive agents …

Activatable cell-penetrating peptides: 15 years of research

H de Jong, KM Bonger, DWPM Löwik - RSC Chemical Biology, 2020 - pubs.rsc.org
An important hurdle for the intracellular delivery of large cargo is the cellular membrane,
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …

Interactions of amphipathic CPPs with model membranes

S Deshayes, K Konate, G Aldrian, F Heitz… - Cell-Penetrating Peptides …, 2011 - Springer
Due to the poor permeability of the plasma membrane, several strategies are designed to
enhance the transfer of therapeutics into cells. Over the last 20 years, small peptides called …

The current role of cell-penetrating peptides in cancer therapy

L Feni, I Neundorf - Peptides and peptide-based biomaterials and their …, 2017 - Springer
Cell-penetrating peptides (CPPs) are a heterogeneous class of peptides with the ability to
translocate across the plasma membrane and to carry attached cargos inside the cell. Two …

Therapeutic potential of cell-penetrating peptides

L Vasconcelos, K Pärn, Ü Langel - Therapeutic delivery, 2013 - Future Science
The ability of cell-penetrating peptides to cross plasma membranes has been used for
various applications, including the delivery of bioactive molecules to inhibit disease …

Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and in vivo studies in drug delivery

JL Zaro, WC Shen - Frontiers of Chemical Science and Engineering, 2015 - Springer
Over the past few decades, cell penetrating peptides (CPPs) have become an important
class of drug carriers for small molecules, proteins, genes and nanoparticle systems. CPPs …

Penetrating peptides: Applications in drug delivery

J Xu, F Wang, L Ye, R Wang, L Zhao, X Yang… - Journal of Drug Delivery …, 2023 - Elsevier
Cell-penetrating peptides (CPPs) have gained prominence in intracellular drug delivery due
to their extremely low toxicity and rapid cell internalization property. They present a powerful …

Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications

A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …