Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis

AA Khan, TJ Quinn, J Hewitt, Y Fan, J Dawson - Age, 2016 - Springer
Serum uric acid (sUA) level may be associated with cognitive impairment/dementia. It is
possible this relationship varies with dementia subtype, particularly between vascular …

[HTML][HTML] Serum uric acid and the risk of dementia: a systematic review and meta-analysis

Z Zhou, S Zhong, Y Liang, X Zhang, R Zhang… - Frontiers in aging …, 2021 - frontiersin.org
Background: This meta-analysis aimed to evaluate the relationship between serum uric acid
(UA) and the risk of dementia and its subtypes. Methods: Embase, PubMed, and Web of …

Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort

AB Alam, A Wu, MC Power, NA West… - Journal of the neurological …, 2020 - Elsevier
Introduction Elevated serum uric acid (SUA) is associated with cardiovascular risk factors,
which often contribute to dementia and dementia-like morbidity, yet several cross-sectional …

[HTML][HTML] Relationship between serum uric acid level and mild cognitive impairment in Chinese community elderly

M Liu, J Wang, J Zeng, Y He - BMC neurology, 2017 - Springer
Background To evaluate the association between SUA levels within a normal to high range
and the risk of mild cognitive impairment (MCI) among community elderly. Methods The …

Serum uric acid and cognitive function and dementia

SM Euser, A Hofman, RGJ Westendorp, MMB Breteler - Brain, 2009 - academic.oup.com
Uric acid is a risk factor of cardiovascular disease, as well as a major natural antioxidant,
prohibiting the occurrence of cellular damage. The relation between uric acid and cognitive …

[HTML][HTML] Serum uric acid levels in patients with Alzheimer's disease: a meta-analysis

X Chen, X Guo, R Huang, Y Chen, Z Zheng, H Shang - PloS one, 2014 - journals.plos.org
Background Serum uric acid (UA) could exert neuro-protective effects against Alzheimer's
disease (AD) via its antioxidant capacities. Many studies investigated serum UA levels in AD …

Uric acid is associated with vascular dementia in Chinese population

Y Xu, Q Wang, R Cui, K Lu, Y Liu, Y Zhao - Brain and behavior, 2017 - Wiley Online Library
Objective Mounting evidence suggests that oxidative stress is involved in the pathogenesis
of vascular dementia (VD). Uric acid (UA) has long been implicated as a critical cause of …

Uric acid and dementia in community-dwelling older persons

C Ruggiero, A Cherubini, F Lauretani… - Dementia and geriatric …, 2009 - karger.com
Background: The biological action of uric acid (UA) in humans is controversial. UA is
considered an antioxidant compound, but preclinical evidence suggests a proinflammatory …

Inverse association between serum uric acid levels and Alzheimer's disease risk

N Du, D Xu, X Hou, X Song, C Liu, Y Chen… - Molecular …, 2016 - Springer
The association between Alzheimer's disease and uric acid levels had gained great interest
in recent years, but there was still lack of definite evidence. A systematic review and meta …

[HTML][HTML] Serum uric acid, Alzheimer-related brain changes, and cognitive impairment

JW Kim, MS Byun, D Yi, JH Lee, SY Jeon… - Frontiers in Aging …, 2020 - frontiersin.org
Background Despite known associations of lower serum uric acid (UA) with Alzheimer's
disease (AD) dementia or AD-related cognitive impairment, little is known regarding the …