Early imaging in heart failure: exploring novel molecular targets

J Shirani, J Narula, WC Eckelman, N Narula… - Journal of nuclear …, 2007 - Springer
Conclusions Noninvasive imaging of neurohumoral upregulation in remodeled myocardium
suggests that an imaging strategy can be developed for predicting the rate of remodeling …

Cardiac molecular imaging to track left ventricular remodeling in heart failure

J Shirani, A Singh, S Agrawal, V Dilsizian - Journal of Nuclear Cardiology, 2017 - Elsevier
Cardiac left ventricular (LV) remodeling is the final common pathway of most primary
cardiovascular diseases that manifest clinically as heart failure (HF). The more advanced the …

Cardiac radionuclide imaging to assess patients with heart failure

MI Travin - Seminars in nuclear medicine, 2014 - Elsevier
Heart failure (HF) is a major problem, with a high prevalence, morbidity, mortality, and cost,
and is expected to become more widespread. Radionuclide imaging currently plays an …

Neuronal dysfunction and medical therapy in heart failure: can an imaging biomarker help to “personalize” therapy?

BS Wessler, JE Udelson - Journal of Nuclear Medicine, 2015 - Soc Nuclear Med
123 I-metaiodobenzylguanidine (123 I-MIBG) imaging is a tool for evaluating one of the
fundamental pathophysiologic abnormalities seen in heart failure (HF), that of an …

Imaging left ventricular remodeling: targeting the neurohumoral axis

J Shirani, V Dilsizian - Nature Clinical Practice Cardiovascular …, 2008 - nature.com
Left ventricular remodeling is a key determinant of the clinical course and outcome of
systolic heart failure. The myocardial renin–angiotensin system (RAS) has been closely …

[HTML][HTML] Molecular Imaging of Heart Failure: An Update and Future Trends

A Saraste, M Ståhle, A Roivainen, J Knuuti - Seminars in Nuclear Medicine, 2024 - Elsevier
Molecular imaging can detect and quantify pathophysiological processes underlying heart
failure, complementing evaluation of cardiac structure and function with other imaging …

Radionuclide noninvasive evaluation of heart failure beyond left ventricular function assessment

A Flotats, I Carrió - Journal of nuclear cardiology, 2009 - Elsevier
The management of patients with heart failure (HF) is challenging and requires the
integration of clinical skills and accurate ancillary tests for the correct diagnosis and …

Molecular imaging targets of cardiac remodeling

J Shirani, V Dilsizian - Current cardiology reports, 2009 - Springer
Left ventricular (LV) remodeling is a major determinant of the clinical course and outcome of
systolic heart failure (HF). Activation of neurohormonal and inflammatory cytokine pathways …

The potential of clinical phenotyping of heart failure with imaging biomarkers for guiding therapies: a focused update

PP Sengupta, CM Kramer, J Narula… - JACC: Cardiovascular …, 2017 - jacc.org
The need for noninvasive assessment of cardiac volumes and ejection fraction (EF) ushered
in the use of cardiac imaging techniques in heart failure (HF) trials that investigated the roles …

Noninvasive imaging of heart failure: neuronal dysfunction and risk stratification

T Higuchi, M Schwaiger - Heart Failure Clinics, 2006 - heartfailure.theclinics.com
Congestive heart failure (CHF) is a clinical syndrome of impaired cardiac contractile function
resulting from structural damage, and is characterized by a vicious cycle in which reduced …