Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein
L Freudzon, RP Norris, AR Hand, S Tanaka… - The Journal of cell …, 2005 - rupress.org
The arrest of meiotic prophase in mouse oocytes within antral follicles requires the G protein
Gs and an orphan member of the G protein–coupled receptor family, GPR3. To determine …
Gs and an orphan member of the G protein–coupled receptor family, GPR3. To determine …
[HTML][HTML] A Gs-linked receptor maintains meiotic arrest in mouse oocytes, but luteinizing hormone does not cause meiotic resumption by terminating receptor-Gs …
RP Norris, L Freudzon, M Freudzon, AR Hand… - Developmental …, 2007 - Elsevier
The maintenance of meiotic prophase arrest in fully grown vertebrate oocytes depends on
the activity of a Gs G-protein that activates adenylyl cyclase and elevates cAMP, and in the …
the activity of a Gs G-protein that activates adenylyl cyclase and elevates cAMP, and in the …
[HTML][HTML] Oocyte-specific expression of Gpr3 is required for the maintenance of meiotic arrest in mouse oocytes
LM Mehlmann - Developmental biology, 2005 - Elsevier
The maintenance of meiotic prophase arrest in mouse oocytes within fully grown follicles,
prior to the surge of luteinizing hormone (LH) that triggers meiotic resumption, depends on a …
prior to the surge of luteinizing hormone (LH) that triggers meiotic resumption, depends on a …
Meiotic Arrest in Human Oocytes Is Maintained by a Gs Signaling Pathway
A DiLuigi, VN Weitzman, MC Pace… - Biology of …, 2008 - academic.oup.com
In mammalian oocytes, the maintenance of meiotic prophase I arrest prior to the surge of LH
that stimulates meiotic maturation depends on a high level of cAMP within the oocyte. In …
that stimulates meiotic maturation depends on a high level of cAMP within the oocyte. In …
[HTML][HTML] The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes
M Hinckley, S Vaccari, K Horner, R Chen, M Conti - Developmental biology, 2005 - Elsevier
In mammalian and amphibian oocytes, the meiotic arrest at the G2/M transition is dependent
on cAMP regulation. Because genetic inactivation of a phosphodiesterase expressed in …
on cAMP regulation. Because genetic inactivation of a phosphodiesterase expressed in …
The Xenopus laevis isoform of G protein-coupled receptor 3 (GPR3) is a constitutively active cell surface receptor that participates in maintaining meiotic arrest in X …
J Deng, S Lang, C Wylie… - Molecular endocrinology, 2008 - academic.oup.com
Oocytes are held in meiotic arrest in prophase I until ovulation, when gonadotropins trigger a
subpopulation of oocytes to resume meiosis in a process termed “maturation.” Meiotic arrest …
subpopulation of oocytes to resume meiosis in a process termed “maturation.” Meiotic arrest …
The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes
The arrest of meiotic prophase in mammalian oocytes within fully grown follicles is
dependent on cyclic adenosine monophosphate (cAMP) regulation. A large part of cAMP is …
dependent on cyclic adenosine monophosphate (cAMP) regulation. A large part of cAMP is …
AG Protein-coupled Receptor Kinase Induces XenopusOocyte Maturation
J Wang, XJ Liu - Journal of Biological Chemistry, 2003 - ASBMB
Several recent studies have suggested that resumption of oocyte meiosis, indicated by
germinal vesicle breakdown or GVBD, involves inhibition of endogenous heterotrimeric G …
germinal vesicle breakdown or GVBD, involves inhibition of endogenous heterotrimeric G …
[HTML][HTML] A role for GPRx, a novel GPR3/6/12-related G-protein coupled receptor, in the maintenance of meiotic arrest in Xenopus laevis oocytes
D Ríos-Cardona, RR Ricardo-González, A Chawla… - Developmental …, 2008 - Elsevier
Progesterone-induced Xenopus laevis oocyte maturation is mediated via a plasma
membrane-bound receptor and does not require gene transcription. Evidence from several …
membrane-bound receptor and does not require gene transcription. Evidence from several …
Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturation
LM Mehlmann - Reproduction, 2005 - rep.bioscientifica.com
Mammalian oocytes grow and undergo meiosis within ovarian follicles. Oocytes are arrested
at the first meiotic prophase, held in meiotic arrest by the surrounding follicle cells until a …
at the first meiotic prophase, held in meiotic arrest by the surrounding follicle cells until a …