SARS-CoV-2 variant Omicron: currently the most complete “escapee” from neutralization by antibodies and vaccines

M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …

Reduced neutralization of SARS-CoV-2 Omicron variant by vaccine sera and monoclonal antibodies

A Wilhelm, M Widera, K Grikscheit, T Toptan, B Schenk… - MedRxiv, 2021 - medrxiv.org
Due to numerous mutations in the spike protein, the SARS-CoV-2 variant of concern
Omicron (B. 1.1. 529) raises serious concerns since it may significantly limit the antibody …

Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination

X Yu, D Wei, W Xu, Y Li, X Li, X Zhang, J Qu, Z Yang… - Cell Discovery, 2022 - nature.com
Dear Editor, As of December, 2021, more than 272 million people have been infected with
SARS-CoV-2. Multiple types of vaccines have been used to build herd immunity for the …

Sensitivity to vaccines, therapeutic antibodies, and viral entry inhibitors and advances to counter the SARS-CoV-2 Omicron variant

H Zhou, M Møhlenberg, JC Thakor… - Clinical microbiology …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and
mutating into newer variants over time, which gain higher transmissibility, disease severity …

SARS-CoV-2 Omicron variant escapes neutralization by vaccinated and convalescent sera and therapeutic monoclonal antibodies

N Ikemura, A Hoshino, Y Higuchi, S Taminishi, T Inaba… - MedRxiv, 2021 - medrxiv.org
The novel SARS-CoV-2 variant, Omicron (B. 1.1. 529) contains about 30 mutations in the
spike protein and the numerous mutations raise the concern of escape from vaccine …

SARS-CoV-2 omicron variant: epidemiological features, biological characteristics, and clinical significance

Y Guo, J Han, Y Zhang, J He, W Yu, X Zhang… - Frontiers in …, 2022 - frontiersin.org
The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern

A Aggarwal, AO Stella, G Walker, A Akerman… - medrxiv, 2021 - medrxiv.org
Genetically distinct viral variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have been recorded since January 2020. Over this time global vaccine programs …

[HTML][HTML] Increased resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7 to antibody neutralization

D Ho, P Wang, L Liu, S Iketani, Y Luo, Y Guo, M Wang… - 2021 - europepmc.org
The Covid-19 pandemic has ravaged the globe, and its causative agent, SARS-CoV-2,
continues to rage. Prospects of ending this pandemic rest on the development of effective …

Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209

B Ju, Q Zheng, H Guo, Q Fan, T Li, S Song, H Sun… - Cell Research, 2022 - nature.com
Dear Editor, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and its variants is still a pandemic raging across the …

SARS‐CoV‐2 Omicron variant: Immune escape and vaccine development

D Ao, T Lan, X He, J Liu, L Chen, DT Baptista‐Hon… - MedComm, 2022 - Wiley Online Library
New genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
constantly emerge through unmitigated spread of the virus in the ongoing Coronavirus …