INTRODUCTION A mechanistic understanding of brain function requires the identification of
distinct cell types in the brain at a molecular, spatial, and functional level. The preoptic …

Determining the spatial organization and morphological characteristics of molecularly
defined cell types is a major bottleneck for characterizing the architecture underpinning …

The hypothalamus is one of the most complex brain structures involved in homeostatic
regulation. Defining cell composition and identifying cell-type-specific transcriptional …

INTRODUCTION Brain function is often compared to an orchestral ensemble, where
subgroups of neurons that have similar activity are analogous to different types of …

In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

The ventral posterior hypothalamus (VPH) is an anatomically complex brain region
implicated in arousal, reproduction, energy balance, and memory processing. However …

The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

To better understand the molecular and cellular differences in brain organization between
human and nonhuman primates, we performed transcriptome sequencing of 16 regions of …

The lateral hypothalamic area (LHA) coordinates an array of fundamental behaviors,
including sleeping, waking, feeding, stress and motivated behavior. The wide spectrum of …

The hypothalamic arcuate–median eminence complex (Arc-ME) controls energy balance,
fertility and growth through molecularly distinct cell types, many of which remain unknown …