Modified forms of low density lipoprotein affect platelet aggregation in vitro

M Aviram - Thrombosis Research, 1989 - Elsevier
Modified forms of low density lipoprotein (LDL) unlike native LDL can lead to macrophage
cholesterol accumulation and foam cell formation. Since platelets interact with both …

Acceleration of platelet aggregability due to modulation of native LDL.

T Kanazawa, H Kaneko, T Uemura, Y Konta… - Circulation …, 1990 - Am Heart Assoc
The aim of this experiment was to clarify whether low density lipoprotein (LDL) causes an
acceleration of platelet aggregability. Native LDL was separated into two fractions by filtered …

Oxidized low-density lipoproteins stimulate adhesion of monocytes to endothelial cells.

XL Niu, XD Yan, ZG Guo - Zhongguo yao li xue bao= Acta …, 1997 - europepmc.org
Aim To study the effects of oxidized low-density lipoproteins (ox-LDL) on the adhesiveness
of monocytes to endothelial cells. Methods LDL was obtained from healthy human plasma …

Degree of oxidation of low density lipoprotein affects expression of CD36 and PPARγ, but not cytokine production, by human monocyte-macrophages

IC Kavanagh, CE Symes, P Renaudin, E Nova… - Atherosclerosis, 2003 - Elsevier
Oxidized low-density lipoprotein (oxLDL) exhibits many atherogenic effects, including the
promotion of monocyte recruitment to the arterial endothelium and the induction of …

Plasma levels of oxidized low density lipoprotein are associated with stable angina pectoris and modalities of acute coronary syndrome

M Imazu, K Ono, F Tadehara, K Kajiwara… - International heart …, 2008 - jstage.jst.go.jp
The role of plasma levels of oxidized low density lipoprotein (OxLDL) in the development of
coronary heart disease (CHD) has not been fully elucidated. We examined the relationship …

Atorvastatin reduces platelet‐oxidized‐LDL receptor expression in hypercholesterolaemic patients

L Puccetti, T Sawamura, AL Pasqui… - European journal of …, 2005 - Wiley Online Library
Abstract Background Oxidized‐LDL (ox‐LDL) are proatherogenic and platelet‐activating
molecules. Atorvastatin reduces platelet activity before cholesterol‐lowering action. CD36 …

The complex link between oxidised low-density lipoprotein and unstable angina

G Niccoli, R Mongiardo, GA Lanza… - Journal of …, 2007 - journals.lww.com
Objective The role of oxidised low-density lipoprotein (ox-LDL) in plaque destabilisation is
controversial; therefore we aimed at comparing plaque and plasma ox-LDL content in stable …

Different Effect of Statins on Platelet Oxidized-LDLReceptor (CD36 and LOX-1) Expressionin Hypercholesterolemic Subjects

F Bruni, AL Pasqui, M Pastorelli… - Clinical and applied …, 2005 - journals.sagepub.com
Hydroxymethyl-glutaryl-CoA-reductase inhibitors (statins) reduce cardiovascular mortality by
decreasing cholesterol as well as by non-lipid-related actions. Oxidized low-density …

Carbamylated low-density lipoproteins induce a prothrombotic state via LOX-1: impact on arterial thrombus formation in vivo

EW Holy, A Akhmedov, T Speer, GG Camici… - Journal of the American …, 2016 - jacc.org
Background: Carbamylation alters low-density lipoprotein (LDL) structure and is thought to
promote vascular inflammation and dysfunction in patients with chronic kidney disease …

Lipoperoxidative injury to macrophages by oxidatively modified low density lipoprotein may play an important role in foam cell formation

SX Liu, M Zhou, Y Chen, WY Wen, MJ Sun - Atherosclerosis, 1996 - Elsevier
Both oxidatively and malondialdehyde modified low density lipoprotein (Ox-LDL and MDA-
LDL) could be recognized by the scavenger receptor and induce intracellular cholesteryl …