Aims T-lymphocytes plays an important role in the pathophysiology of acute coronary
syndromes. T-cell activation in vitro by pro-inflammatory cytokines may lead to functional …

The in vitro oxidation of low-density lipoprotein (LDL) by hypochlorous acid produces a
modified form (HOCl-LDL) capable of stimulating platelet function. We now report that HOCl …

Conflicting reports exist about the effects of mildly or extensively oxidized low density
lipoproteins (LDLs) on the reactivity of human platelets. This platelet response is mainly …

Objective—The interaction of platelets with low density lipoprotein (LDL) contributes to the
development of cardiovascular disease. Platelets are activated by native LDL (nLDL) …

Background Oxidized LDL (ox-LDL) promotes vasoconstriction and platelet activation. The
present study was undertaken to determine the involvement of the l-arginine–nitric oxide …

Circulating oxidized LDL (oxLDL) levels are strongly correlated to LDL-cholesterol (LDL-c)
and apolipoprotein-B100 (apoB100), making it difficult to disentangle their independent …

The oxidation of low-density lipoprotein (LDL) is thought to be a major contributor to the
development of atherosclerosis and considerable evidence has accumulated showing that …

To clarify the effect of concentration polarization of oxidative modification of low-density
lipoproteins (ox-LDLs) on human smooth muscle cells (SMCs), the proliferation, ox-LDL …

Central to the pathogenesis of atherosclerosis is an abnormally functioning endothelium and
a consequent loss of vascular integrity. These abnormalities may be induced by …

The effects of native and oxidized low density lipoproteins on platelet aggregability remain
controversial despite numerous studies. In the current investigation, effects of native …