Aims Oxidative modification of low‐density lipoprotein (LDL) is believed to be a key step in
the genesis of atherosclerotic lesions. The presence of small, dense LDL is associated with …

Oxidized low-density lipoproteins (ox-LDLs) induce vasoconstriction and platelet activation,
and high-density lipoproteins (HDLs) reverse these effects of ox-LDL. To determine the …

Oxidized low-density lipoprotein (OxLDL) is a well-known risk marker for cardiovascular
diseases. OxLDL has shown a variety of proatherogenic properties in experiments …

Accumulating evidence indicates that oxidized low‐density lipoprotein (OxLDL) is a useful
marker for cardiovascular disease. The uptake of OxLDL by scavenger receptors leads to …

Oxidized LDL (ox-LDL) play an important role in atherogenesis. It has been demonstrated in
our laboratory that ox-LDL play a cytotoxic effect on cultured macrophages. This cell death …

OBJECTIVE--To assess whether the extent of LDL oxidation influences its cytotoxic effects,
thus contributing to its atherogenic potential. DESIGN AND SETTING--The effects of native …

A high concentration of low-density lipoproteins (LDLs) in circulation has been well-known
as a major risk factor for cardiovascular diseases. The presence of oxidized LDLs (oxLDLs) …

Aim: To investigate whether HDL 2 can inhibit further oxidative modification of partially
oxidized LDL (ox-LDL) by interrupting the chain oxidation reaction after lipid hydroperoxides …

Background Activated vascular cells produce submicron prothrombotic and proinflammatory
microparticle vesicles. Atherosclerotic plaques contain high levels of microparticles. Plasma …

Background—Flowing erythrocytes and platelets are separated from the luminal endothelial
cell (EC) surface by a 0.5-μm-wide space named the endothelial surface layer. We …