Molecular determinants of oxidized low-density lipoprotein–induced leukocyte adhesion and microvascular dysfunction

L Liao, RM Starzyk, DN Granger - Arteriosclerosis, thrombosis, and …, 1997 - Am Heart Assoc
Oxidized low-density lipoproteins (oxLDL) have been implicated in the leukocyte recruitment
and microvascular dysfunction associated with atherosclerosis. The objectives of this study …

Hypochlorite-oxidized LDL induces intraplatelet ROS formation and surface exposure of CD40L—A prominent role of CD36

A Assinger, F Koller, W Schmid, M Zellner, E Koller… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: OxLDL represents a central player in atherogenesis and has been shown to
activate human blood platelets. In light of the pivotal role of CD40L in inflammation, it was …

Functional morphological alterations of human blood platelets induced by oxidized low density lipoprotein

B Zhao, R Dierichs, B Liu, M Holling-Rauβ - Thrombosis research, 1994 - Elsevier
The effect of oxidized low density lipoprotein (LDL) on the functional morphology of human
platelets in vitro was studied by means of transmission electron microscopy. The washed …

Small dense LDL enhances THP-1 macrophage foam cell formation

M Tani, A Kawakami, Y Mizuno, R Imase… - … of Atherosclerosis and …, 2011 - jstage.jst.go.jp
Aim: Increased levels of small dense low-density lipoproteins (sd-LDL) have been reported
more atherogenic compared to total low-density lipoprotein (LDL); however, no definitive …

Plasma very-low-density lipoprotein, low-density lipoprotein, and high-density lipoprotein oxidative modification induces procoagulant profiles in endogenous …

H Bai, BW Liu, ZY Deng, T Shen, DZ Fang… - Free Radical Biology …, 2006 - Elsevier
This study was to investigate whether oxidatively modified lipoproteins were associated with
changes of pro-and anticoagulant profiles in hypertriglyceridemic subjects. Plasma VLDL …

Concentration polarization of oxidative modification of low-density lipoproteins: its effect on oxidative modification of low-density lipoprotein uptake and apoptosis of …

Z Ding, Y Fan, X Deng - ASAIO Journal, 2010 - journals.lww.com
There is increasing evidence suggesting that oxidative modification of low-density
lipoprotein (ox-LDL) in the vessel wall plays a crucial role in the initiation and progression of …

Human cardiac microvascular and macrovascular endothelial cells respond differently to oxidatively modified LDL

M Gräfe, W Auch-Schwelk, H Hertel, D Terbeek… - Atherosclerosis, 1998 - Elsevier
Oxidation of low density lipoproteins (LDL) is considered a key event in the pathogenesis of
atherosclerotic lesions. Disturbed generation of coagulatory and anticoagulatory factors by …

Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI

M Valiyaveettil, N Kar, MZ Ashraf… - Blood, The Journal …, 2008 - ashpublications.org
Numerous studies have reported the presence of oxidatively modified high-density
lipoprotein (OxHDL) within the intima of atheromatous plaques as well as in plasma; …

Oxidized LDL damages endothelial cell monolayer and promotes thrombocyte adhesion

B Liu, A Sidiropoulos, B Zhao… - American journal of …, 1998 - Wiley Online Library
The influence of oxidized low density lipoprotein (LDL) on a human endothelial cell
monolayer was examined. The resulting contraction of the oxidized LDL‐damaged …

Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk

S Tsimikas, JL Witztum - Circulation, 2001 - Am Heart Assoc
The hypothesis that oxidized LDL (ox-LDL) is neces-sary, if not obligatory, in the
development of atherosclerotic lesions was formulated 20 years ago with the seminal …